Description
Demeton is a light brown liquid with an odorof sulfur compounds; Freezing/Melting point #213℃.Molecular weight = 516.92; Boiling point =134℃ at2 mmHg at 20℃; Flash point =45℃; Explosive limits:LEL = 1%; UEL = 5.3%. Hazard Identification (based onNFPA-704 M Rating System): Health 3, Flammability 2,Reactivity 0. Insoluble in water.
Chemical Properties
Demeton is a light brown liquid with an odor
of sulfur compounds; freezing/melting point ≤‐13
C
Uses
Demeton-O is an organophosphorus pesticide found in some imported crops and fruits samples.
Production Methods
Demeton-O was commercially produced through esterification of O,O-diethyl phosphorothioic acid with 2-(ethylthio)ethanol. The process typically involved preparing the phosphorothioic acid derivative, then reacting it with the thioalcohol under controlled conditions in the presence of a catalyst to form the thiono ester. This reaction was carried out in an organic solvent at moderate temperatures, followed by purification steps such as vacuum distillation to obtain technical-grade Demeton-O.
Definition
ChEBI: Demeton-O is an organic thiophosphate.
Mechanism of action
Systemic with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
Potential Exposure
A potential danger to those involved
in the manufacture, formulation, and application of this
systemic insecticide and acaricide.
First aid
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Speed in removing material from skinis of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If thischemical has been inhaled, remove from exposure, beginrescue breathing (using universal precautions, includingresuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Effects may be delayed; medical observation isrecommended
storage
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with demetonyou should be trained on its proper handling and storage. Aregulated, marked area should be established where thischemical is handled, used, or stored in compliance withOSHA Standard 1910.1045. Before entering confined spacewhere this chemical may be present, check to make surethat an explosive concentration does not exist. Store inDemeton 861tightly closed containers in a cool, well-ventilated areaaway from oxidizers, strong bases, water, soluble mercury,and other pesticides. Where possible, automatically pumpliquid from drums or other storage containers to processcontainers.
Shipping
UN3278 Organophosphorus compound, liquid,
toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous
materials, Hazard Technical Name Required, Potential
Inhalation Hazard (Special Provision 5). UN3017
Organophosphorus pesticides, liquid, toxic, flammable,
flash point not , 23
C, Hazard class: 6.1; Labels: 6.1-
Poisonous materials, 3-Flammable liquid. UN2810 Toxic
liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-
Poisonous materials, Technical Name Required.
Incompatibilities
May form explosive mixture with air.
Strong oxidizers, strong bases, soluble mercury, other
pesticides, and water.
Waste Disposal
The thiono-and thiolo-isomers of
this mixture are 50% hydrolyzed in 75 minutes and 0.85 min-
ute, respectively @ 20℃
and pH 13. At pH 9 and 70 ℃
, the
half-life of Demeton is 1.25 hour, but an pH 1-5 it is over
11 hours. Sand and rushed limestone may be added together
with a flammable solvent; the resultant mixture may be burned
in a furnace with afterburner and alkaline scrubber
.In
accordance with 40CFR165, follow recommendations for the
disposal of pesticides and pesticide containers. Must be dis-
posed properly by following package label directions or by
contacting your local or federal environmental control agency,
or by contacting your regional EPA office.
Pesticide Type
Insecticide; Acaricide
