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LAVENDUSTIN A

LAVENDUSTIN A Structure
LAVENDUSTIN A
  • CAS No.125697-92-9
  • Chemical Name:LAVENDUSTIN A
  • CBNumber:CB2135704
  • Molecular Formula:C21H19NO6
  • Formula Weight:381.38
  • MOL File:125697-92-9.mol
LAVENDUSTIN A Property
  • Melting point 205-215 °C
  • Boiling point 741.7±60.0 °C(Predicted)
  • Density 1.495±0.06 g/cm3(Predicted)
  • RTECS DG8578950
  • storage temp. −20°C
  • solubility DMSO: soluble
  • pka 2.31±0.10(Predicted)
  • form crystalline
  • color Yellow to brown
  • Sensitive Air Sensitive
  • Stability Moisture Sensitive: Hygroscopic
  • CAS DataBase Reference 125697-92-9(CAS DataBase Reference)
  • FDA UNII 3Y0G32G2RV
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :37/39-26
  • WGK Germany  :3
  • HS Code  :29225000
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
LAVENDUSTIN A Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: 428150
  • Product name : Lavendustin A - CAS 125697-92-9 - Calbiochem
  • Purity: A cell-permeable, reversible, and substrate competitive inhibitor of EGF receptor tyrosine kinase and p60c-src with little effect on protein kinase A
  • Packaging: 1MG
  • Price: ₹19050
  • Updated: 2022/06/14
  • Buy: Buy

LAVENDUSTIN A Chemical Properties,Usage,Production

  • Description Lavendustin A is a selective inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase (IC50 = 11 nM) that was first isolated from a Streptomyces culture filtrate. It does not inhibit protein kinase A (PKA), PKC, or PI3K (IC50s > 100 μM). It has been used to differentiate rat mesenchymal stem cells, to inhibit NMDA-stimulated cGMP production, and to inhibit VEGF-induced angiogenesis.
  • Chemical Properties Off-White Solid
  • Uses A potent tyrosine kinase inhibitor. Inhibition is competitive with ATP and is noncompetitive with the peptide.
  • Definition ChEBI: 5-[(2,5-dihydroxyphenyl)methyl-[(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic acid is an aromatic amine.
  • Biological Activity Potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC 50 = 11 nM). Inhibits p60 c-src with an IC 50 of 500 nM and is selective over PKA, PKC and PI 3-kinase (IC 50 > 100 μ M).
  • target EGFR | PKC | PI3K | Calcium Channel
LAVENDUSTIN A Preparation Products And Raw materials
Raw materials
Preparation Products
LAVENDUSTIN A Suppliers
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LAVENDUSTIN A Spectrum
125697-92-9, LAVENDUSTIN ARelated Search:
  • Tyrosine Kinase Inhibitors
  • Inhibitors
  • All Inhibitors
  • Miscellaneous Natural Products
  • 抑制剂
  • 小分子API
  • 分析试剂标准品
  • Tyrosine Kinase (TK)
  • Receptor Tyrosine Kinase Inhibitors
  • Kinase/Phosphatase Biology
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • LAVENDUSTIN A,TYROSINE KINASE抑制剂
  • 化合物LAVENDUSTIN A
  • 薰草菌素A
  • 薰草菌素
  • 5-[[(2,5-二羟苯基)甲基][(2 -羟基苯基)甲基]氨基]-2-羟基苯甲酸
  • 125697-92-9
  • Lavendustin A, tyrosine kinase inhibitor
  • LAVENDUSTIN A USP/EP/BP
  • RG-14355;NSC 678027
  • Lavendustin A - CAS 125697-92-9 - Calbiochem
  • Benzoic acid,5-[[(2,5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxy-
  • NSC 678027
  • Lavendustin A,98%
  • 5-[(2,5-Dihydroxybenzyl)(2-hydroxybenzyl)amino]-2-hydroxybenzoic acid
  • 5-[[(2,5-DIHYDROXYPHENYL)METHYL][(2-HYDROXYPHENYL)METHYL]AMINO]-2-HYDROXYBENZOIC ACID
  • 5-AMINO-[(N-2,5-DIHYDROXYBENZYL)-N'-2-HYDROXYBENZYL]SALICYLIC ACID
  • LAVENDUSTIN A
  • RG14355

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