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4-Hydroxythiobenzamide

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4-Hydroxythiobenzamide Structure
4-Hydroxythiobenzamide
  • CAS No.25984-63-8
  • Chemical Name:4-Hydroxythiobenzamide
  • CBNumber:CB1314575
  • Molecular Formula:C7H7NOS
  • Formula Weight:153.2
  • MOL File:25984-63-8.mol
4-Hydroxythiobenzamide Property
  • Melting point 181-185℃
  • Boiling point 320.4±44.0 °C(Predicted)
  • Density 1.338±0.06 g/cm3(Predicted)
  • storage temp. Keep in dark place,Inert atmosphere,Room temperature
  • solubility DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • pka 9.24±0.26(Predicted)
  • color Light Yellow
  • InChI InChI=1S/C7H7NOS/c8-7(10)5-1-3-6(9)4-2-5/h1-4,9H,(H2,8,10)
  • InChIKey VDTNKXSVUGXUOJ-UHFFFAOYSA-N
  • SMILES C1(C(N)=S)=CC=C(O)C=C1
  • CAS DataBase Reference 25984-63-8(CAS DataBase Reference)
  • FDA UNII ZZ8JR2736Y
  • UNSPSC Code 12352200
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H302-H335
  • Precautionary statements P280h-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
4-Hydroxythiobenzamide Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: H1308
  • Product name : 4-Hydroxythiobenzamide
  • Purity: 
  • Packaging: 5G
  • Price: ₹5000
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H1308
  • Product name : 4-Hydroxythiobenzamide
  • Purity: 
  • Packaging: 25G
  • Price: ₹15900
  • Updated: 2022/05/26
  • Buy: Buy

4-Hydroxythiobenzamide Chemical Properties,Usage,Production

  • Uses 4-Hydroxythiobenzamide(25984-63-8) is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.
  • Chemical Properties 4-Hydroxythiobenzamide has an appearance ranging from light orange to yellow to green, powder to crystalline, melting point 192 °C, soluble in methanol.
  • Uses febuxostat intermediate
  • Uses 4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.
  • Synthesis 4-Hydroxythiobenzamide is an important intermediate of Febuxostat, a new anti-gout drug. A patent discloses a method for preparing p-hydroxythiobenzamide. Specifically, a certain amount of water, p-cyanophenol, sodium hydrosulfide, and secondary amine are mixed evenly. At a specific temperature, an organic weak acid is added dropwise. After the reaction is completed, the mixture is filtered, and the filter cake is dried to obtain 4-Hydroxythiobenzamide.
    4-HYDROXYTHIOBENZAMIDE
4-Hydroxythiobenzamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global(565)Suppliers
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4-Hydroxythiobenzamide Spectrum
25984-63-8, 4-HydroxythiobenzamideRelated Search:
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  • C7H7NOS
  • C7H8NOS
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