ChemicalBook > CAS DataBase List > Propargyl-PEG8-t-butyl ester
Propargyl-PEG8-t-butyl ester
Propargyl-PEG8-t-butyl ester
- CAS No.2055014-96-3
- Chemical Name:Propargyl-PEG8-t-butyl ester
- CBNumber:CB13134215
- Molecular Formula:C24H44O10
- Formula Weight:492.6
- MOL File:2055014-96-3.mol
Propargyl-PEG8-t-butyl ester Property
- Boiling point 528.4±45.0 °C(Predicted)
- Density 1.064±0.06 g/cm3(Predicted)
- solubility Soluble in Water, DMSO, DCM, DMF
- form Liquid
- color Colorless to light yellow
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319-H401
- Precautionary statements P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Propargyl-PEG8-t-butyl ester Chemical Properties,Usage,Production
- Description Propargyl-PEG8-t-butyl ester is a PEG reagent with an alkyne group and a t-butyl group. The alkyne group enables the formation of triazole linkage with azide-bearing compounds or biomolecules; copper is required as a catalyst. The t-butyl group can be hydrolyzed under acidic conditions. The hydrophicility of the molecule is improved by having 8 units of PEG.
- Uses Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG8-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- IC 50 PEGs; Alkyl/ether
- References [1] Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.
Propargyl-PEG8-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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- peg
- 抑制剂
- PEG系列产品-Propargy-PEG系列
- 助剂
- C24H44O10
- 1,1-二甲基乙基 4,7,10,13,16,19,22,25-辛氧二十八烷-27-烯酸酯
- 化合物 PROPARGYL-PEG8-BOC
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- 2055014-96-3
- 4,7,10,13,16,19,22,25-octaoxaco-27-tert-butyl alkynate
- Propargyl-PEG7-C2-COOtBu
- Propargyl-PEG7-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaoctacos-27-ynoic acid, 1,1-dimethylethyl ester
- Propargyl-PEG8-t-Bu Ester
- 4,7,10,13,16,19,22,25-Octaoxaoctacos-27-ynoic acid, 1,1-dimethylethyl ester
- Propargyl-PEG8-Boc
- Propargyl-PEG7-CH2CH2COOtBu
- CAS_2055014-96-3
- Propargyl-PEG8-COOtBu
- Propargyl-PEG8-t-butyl ester