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Propargyl-PEG7-t-butyl ester

Propargyl-PEG7-t-butyl ester Structure
Propargyl-PEG7-t-butyl ester
  • CAS No.1818294-29-9
  • Chemical Name:Propargyl-PEG7-t-butyl ester
  • CBNumber:CB73062637
  • Molecular Formula:C22H40O9
  • Formula Weight:448.55
  • MOL File:1818294-29-9.mol
Propargyl-PEG7-t-butyl ester Property
  • Boiling point 494.3±40.0 °C(Predicted)
  • Density 1.059±0.06 g/cm3(Predicted)
  • solubility Soluble in DCM, DMF
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Propargyl-PEG7-t-butyl ester Chemical Properties,Usage,Production

  • Description Propargyl-PEG7-t-butyl ester comprises a propargyl group and a t-butyl protected carboxyl group. The propargyl group reacts with azide compounds via copper catalyzed Click Chemistry to form a stable triazole linkage. Under acidic conditions, the carboxyl group can be deprotected. The hydrophilic PEG units enhance solubility of the molecule in aqueous media.
  • Uses Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG7-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • IC 50 PEGs; Alkyl/ether
  • References [1] Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.
Propargyl-PEG7-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Propargyl-PEG7-t-butyl ester Spectrum
1818294-29-9, Propargyl-PEG7-t-butyl esterRelated Search:
  • PEG系列产品-Propargy-PEG系列
  • C22H40O9
  • 3-[2-[2-[2-[2-[2-[2-(2-丙-2-炔氧基乙氧基)乙氧基]乙氧基]-乙氧基]乙氧基丙酸叔丁酯
  • 4,7,10,13,16,19,22-七氧杂二十五碳-24-炔酸叔丁酯
  • 丙炔-七聚乙二醇-丙酸叔丁酯
  • 丙炔基-六聚乙二醇-丙酸叔丁酯
  • 1818294-29-9
  • tert-butyl 3-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
  • tert-Butyl 4,7,10,13,16,19,22-heptaoxapentacos-24-ynoate
  • Propargyl-PEG6-C2-COOtBu
  • Propargyl-PEG6-CH2CH2COOtBu/4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid, 1,1-dimethylethyl ester
  • PropargylPEG7-tBu ester
  • Propargyl-PEG7-Boc
  • CAS_1818294-29-9
  • 4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid, 1,1-dimethylethyl ester
  • Propargyl-PEG7-COOtBu
  • Propargyl-PEG6-CH2CH2COOtBu
  • Propargyl-PEG7-t-butyl ester

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