ethyl 3-(2,2-dichlorovinyl)-2,2-dimethyl-1-cyclopropanecarboxylate

Chemical Properties

Ethyl permethrin is a colorless and transparent liquid, bp93～94℃/101pa, 78～88℃/27pa, n²⁰_D 1.4833, relative density 1.1170, insoluble In water, soluble in benzene, toluene, chloroform and other organic solvents.

Uses

Ethyl 3-(2,2-dichlorovinyl)-2,2-dimethyl-1-cyclopropanecarboxylate is an important intermediate of pyrethroids and can be used to prepare permethrin, cypermethrin, beta-cypermethrin, transfluthrin, cyfluthrin, etc.

Synthesis

Condensation of isobutylene and chloral under the catalysis of AlCl₃ to form a enol, then acetylation, zinc powder reduction and acid-catalyzed isomerization to obtain conjugated dienes, and finally combined with diazoacetic acid Methyl ester (ethyl ester) reacts under the catalysis of copper powder to obtain ethyl 3-(2,2-dichlorovinyl)-2,2-dimethyl-1-cyclopropanecarboxylate.