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2-Chloro-4,5-diaminopyrimidine

2-Chloro-4,5-diaminopyrimidine Structure
2-Chloro-4,5-diaminopyrimidine
  • CAS No.14631-08-4
  • Chemical Name:2-Chloro-4,5-diaminopyrimidine
  • CBNumber:CB0754718
  • Molecular Formula:C4H5ClN4
  • Formula Weight:144.56
  • MOL File:14631-08-4.mol
2-Chloro-4,5-diaminopyrimidine Property
  • Melting point 220 °C (decomp)
  • Boiling point 417.9±25.0 °C(Predicted)
  • Density 1.564±0.06 g/cm3(Predicted)
  • storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
  • pka 3.61±0.10(Predicted)
  • CAS DataBase Reference 14631-08-4(CAS DataBase Reference)
  • FDA UNII TW5LFP3QGS
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :22-36-43
  • Safety Statements  :26-36/37
  • HS Code  :2933599590
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

2-Chloro-4,5-diaminopyrimidine Chemical Properties,Usage,Production

  • Synthesis A mixture of 2-chloro-5-nitropyrimidin-4-amine (1.0 g, 5.7 mmol) and SnCl2·2H2O (5.2 g, 22.9 mmol) in EtOH (55 mL) under N2 was heated to 80 °C and stirred for two hours. The mixture was then concentrated under reduced pressure. EtOAc and Celite were added to the residue, and the mixture was basified with saturated Na2CO3 (aq.) to pH 9- 10. The mixture was filtered through a pad of Celite and washed with EtOAc. The organic layer was separated, washed with brine, dried (Na2SO4), and concentrated in a vacuum. The residue was purified on ISCO (20 g silica gel column, EtOAc/hexanes 0~100 per cent) to give 2-Chloro-4,5-diaminopyrimidine (0.41 g 49 per cent).
2-Chloro-4,5-diaminopyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-4,5-diaminopyrimidine Suppliers
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2-Chloro-4,5-diaminopyrimidine Spectrum
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  • IFLAB-BB F1371-0155

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