ChemicalBook > CAS DataBase List > FORSYTHOSIDE A
FORSYTHOSIDE A
FORSYTHOSIDE A
- CAS No.79916-77-1
- Chemical Name:FORSYTHOSIDE A
- CBNumber:CB0699291
- Molecular Formula:C29H36O15
- Formula Weight:624.59
- MOL File:79916-77-1.mol
FORSYTHOSIDE A Property
- Melting point >127°C (subl.)
- Boiling point 911.9±65.0 °C(Predicted)
- Density 1.60±0.1 g/cm3(Predicted)
- storage temp. 2-8°C
- solubility DMSO (Slightly), Methanol (Slightly)
- form Solid
- pka 9.31±0.10(Predicted)
- color Off-White to Light Beige
- CAS DataBase Reference 79916-77-1
- FDA UNII OUH5BQ893P
- UNSPSC Code 41116107
- NACRES NA.24
Safety
- HS Code :29389090
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P305+P351+P338
FORSYTHOSIDE A Chemical Properties,Usage,Production
-
Overview
Forsythiaside A is the phenylethanol glycoside component isolated from Forsythia. It has pharmacological effects such as antibacterial, antiviral, antioxidant, anti-infective and antipyretic. It is mainly used for content determination, identification, and pharmacological experiment and so on.
- Chemical Properties This product appears as white crystalline powder. It is easily soluble in water, ethanol and methanol, but insoluble in ether and chloroform.
- Pharmacological effects Forsythoside A has not only antibacterial, anti-infective and antipyretic effects, but also good anti-virus and antioxidant effects.
- Preparation Extract 40 g of crushed forsythia leaves with 1200 mL 55% ethanol (volume fraction) at 74 ° C for 50 min, filter and extract twice. The filtrate was combined and concentrated under reduced pressure at 50 °C to recycle the ethanol, obtaining 665 mL of concentrated solution. 35 mL of absolute ethanol was added to give a forsythia leaf extract containing 5% ethanol (volume fraction). The forsythia leaf extract was adsorbed on a 2.6 cm x 25 cm AB-8 resin column and eluted with 50% ethanol to obtain a forsythia leaf extract. The extract of forsythia leaf was extracted for three times with water-saturated n-butanol. Recycle the n-butanol, and dry to obtain crude product. The crude product was separated in 8 cm x 50 cm C18 reverse phase silica gel column chromatography through elution with 30% methanol. Collect the eluent and obtain the pure compound of forsythoside A under reduced pressure.
- Application It can be used for content determination, identification and pharmacological experiments.
- Uses Forsythoside A is used as an antiinflammatory agent in traditional Chinese medicine.
- Definition ChEBI: Forsythiaside is a hydroxycinnamic acid.
- Biological Activity extracted from forsythia suspense (thunb.) vahl dried fruit;store the product in sealed, cool and dry condition
-
in vivo
Forsythiaside A (15-60 mg/kg; single dose; oral) improves OVA-induced asthma models in mice, dose-dependently activates Nrf2/HO-1 signaling, and attenuates OVA-induced lung histopathology[3].
FORSYTHOSIDE A Preparation Products And Raw materials
Raw materials
Preparation Products
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79916-77-1, FORSYTHOSIDE ARelated Search:
- standardized herbal extract
- reference standards from Chinese medicinal herbs (TCM).
- phytochemical
- pharmaceutical intermediate
- chemical reagent
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- 连翘酯苷A,10 MM DMSO 溶液
- FORSYTHIASIDE|||FORSYTHOSIDE A|||连翘脂苷A|||连翘酯苷A
- 标准品对照品】FORSYTHOSIDE A
- (E)-(2R,3S,4R,5R,6R)-6-(3,4-二羟基甲氧基)-4,5-二羟基-2-((((2R,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)甲基)四氢-2H-吡喃-3-基 (3,4-二羟基苯基)丙烯酸酯
- 连翘酯苷 连翘酯苷A
- 连翘脂苷A(连翘酯苷A)
- 连翘酯苷A(分析标准品)
- 连翘酯苷A(连翘酯素)
- 连翘酯苷A, 来源于连翘
- 连翘酯苷A对照品,
- FORSYTHOSIDE A 连翘酯苷A
- 连翘脂苷A(连翘脂苷)
- 连翘脂素A
- 连翘脂素/连翘脂苷A/连翘酯苷A
- 连翘酯苷A(标准品)
- 连翘酯苷 A
- 连翘脂苷(连翘酯苷A)
- 连翘脂素
- 连翘脂苷A
- 79916-77-1
- Forsythoside A - ex luteina Forsythia suspensa
- Forsythiaside A, 10 mM in DMSO
- Forsythoside A-RM
- Forsythiaside|||Forsythoside A
- Forsythiaside A
- Forsythiaside
- [(E)-(5-nitrofuran-2-yl)methylideneamino
- (E)-(2R,3S,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-4,5-dihydroxy-2-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3-yl 3-(3,4-dihydroxyphenyl)acrylate
- [(2R,3S,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-4,5-dihydroxy-2-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
- β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 6-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
- Forsythoside A 79916-77-1
- Forsythoside A, 98%, from Forsythia suspensa
- b-D-Glucopyranoside,2-(3,4-dihydroxyphenyl)ethyl 6-O-(6-deoxy-a-L-Mannopyranosyl)-,4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
- FORSYTHOSIDE A