Overview Chemical Properties Pharmacological effects Preparation Application
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FORSYTHOSIDE A

Overview Chemical Properties Pharmacological effects Preparation Application
FORSYTHOSIDE A Structure
FORSYTHOSIDE A
  • CAS No.79916-77-1
  • Chemical Name:FORSYTHOSIDE A
  • CBNumber:CB0699291
  • Molecular Formula:C29H36O15
  • Formula Weight:624.59
  • MOL File:79916-77-1.mol
FORSYTHOSIDE A Property
  • Melting point >127°C (subl.)
  • Boiling point 911.9±65.0 °C(Predicted)
  • Density 1.60±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • pka 9.31±0.10(Predicted)
  • color Off-White to Light Beige
  • CAS DataBase Reference 79916-77-1
  • FDA UNII OUH5BQ893P
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • HS Code  :29389090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

FORSYTHOSIDE A Chemical Properties,Usage,Production

  • Overview Forsythiaside A is the phenylethanol glycoside component isolated from Forsythia. It has pharmacological effects such as antibacterial, antiviral, antioxidant, anti-infective and antipyretic. It is mainly used for content determination, identification, and pharmacological experiment and so on. Forsythiaside A
  • Chemical Properties This product appears as white crystalline powder. It is easily soluble in water, ethanol and methanol, but insoluble in ether and chloroform.
  • Pharmacological effects Forsythoside A has not only antibacterial, anti-infective and antipyretic effects, but also good anti-virus and antioxidant effects.
  • Preparation Extract 40 g of crushed forsythia leaves with 1200 mL 55% ethanol (volume fraction) at 74 ° C for 50 min, filter and extract twice. The filtrate was combined and concentrated under reduced pressure at 50 °C to recycle the ethanol, obtaining 665 mL of concentrated solution. 35 mL of absolute ethanol was added to give a forsythia leaf extract containing 5% ethanol (volume fraction). The forsythia leaf extract was adsorbed on a 2.6 cm x 25 cm AB-8 resin column and eluted with 50% ethanol to obtain a forsythia leaf extract. The extract of forsythia leaf was extracted for three times with water-saturated n-butanol. Recycle the n-butanol, and dry to obtain crude product. The crude product was separated in 8 cm x 50 cm C18 reverse phase silica gel column chromatography through elution with 30% methanol. Collect the eluent and obtain the pure compound of forsythoside A under reduced pressure.
  • Application It can be used for content determination, identification and pharmacological experiments.
  • Uses Forsythoside A is used as an antiinflammatory agent in traditional Chinese medicine.
  • Definition ChEBI: Forsythiaside is a hydroxycinnamic acid.
  • Biological Activity extracted from forsythia suspense (thunb.) vahl dried fruit;store the product in sealed, cool and dry condition
  • in vivo

    Forsythiaside A (15-60 mg/kg; single dose; oral) improves OVA-induced asthma models in mice, dose-dependently activates Nrf2/HO-1 signaling, and attenuates OVA-induced lung histopathology[3].

FORSYTHOSIDE A Preparation Products And Raw materials
Raw materials
Preparation Products
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    BOC Sciences
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FORSYTHOSIDE A Spectrum
79916-77-1, FORSYTHOSIDE ARelated Search:
  • standardized herbal extract
  • reference standards from Chinese medicinal herbs (TCM).
  • phytochemical
  • pharmaceutical intermediate
  • chemical reagent
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  • 连翘酯苷A,10 MM DMSO 溶液
  • FORSYTHIASIDE|||FORSYTHOSIDE A|||连翘脂苷A|||连翘酯苷A
  • 标准品对照品】FORSYTHOSIDE A
  • (E)-(2R,3S,4R,5R,6R)-6-(3,4-二羟基甲氧基)-4,5-二羟基-2-((((2R,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)甲基)四氢-2H-吡喃-3-基 (3,4-二羟基苯基)丙烯酸酯
  • 连翘酯苷 连翘酯苷A
  • 连翘脂苷A(连翘酯苷A)
  • 连翘酯苷A(分析标准品)
  • 连翘酯苷A(连翘酯素)
  • 连翘酯苷A, 来源于连翘
  • 连翘酯苷A对照品,
  • FORSYTHOSIDE A 连翘酯苷A
  • 连翘脂苷A(连翘脂苷)
  • 连翘脂素A
  • 连翘脂素/连翘脂苷A/连翘酯苷A
  • 连翘酯苷A(标准品)
  • 连翘酯苷 A
  • 连翘脂苷(连翘酯苷A)
  • 连翘脂素
  • 连翘脂苷A
  • 79916-77-1
  • Forsythoside A - ex luteina Forsythia suspensa
  • Forsythiaside A, 10 mM in DMSO
  • Forsythoside A-RM
  • Forsythiaside|||Forsythoside A
  • Forsythiaside A
  • Forsythiaside
  • [(E)-(5-nitrofuran-2-yl)methylideneamino
  • (E)-(2R,3S,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-4,5-dihydroxy-2-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3-yl 3-(3,4-dihydroxyphenyl)acrylate
  • [(2R,3S,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-4,5-dihydroxy-2-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
  • β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 6-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
  • Forsythoside A 79916-77-1
  • Forsythoside A, 98%, from Forsythia suspensa
  • b-D-Glucopyranoside,2-(3,4-dihydroxyphenyl)ethyl 6-O-(6-deoxy-a-L-Mannopyranosyl)-,4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
  • FORSYTHOSIDE A