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Acetylspiramycin

Acetylspiramycin Structure
Acetylspiramycin
  • CAS No.24916-51-6
  • Chemical Name:Acetylspiramycin
  • CBNumber:CB0383628
  • Molecular Formula:C45H76N2O15
  • Formula Weight:885.09
  • MOL File:24916-51-6.mol
Acetylspiramycin Property
  • Melting point 130-1330C
  • alpha D20 -86°
  • Boiling point 916.7±65.0 °C(Predicted)
  • Density 1.21±0.1 g/cm3(Predicted)
  • storage temp. Sealed in dry,Store in freezer, under -20°C
  • solubility DMSO (Slightly, Sonicated), Methanol (Very Slightly, Heated)
  • form Solid
  • pka 13.06±0.70(Predicted)
  • color White to Light Yellow
  • CAS DataBase Reference 24916-51-6
  • FDA UNII 05298J5WMU
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Acetylspiramycin Chemical Properties,Usage,Production

  • Chemical Properties Crystalline Solid
  • Uses Antibiotic substance classified in the erythromycin-carbomycin group
  • Definition ChEBI: A macrolide antibiotic produced by various Streptomyces species.
  • in vivo

    Acetylspiramycin (25-200 mg/kg/day; Oral gavage (p.o.); 7 days) can significantly enhance the lymphocyte proliferation response of CBA/H mice to PHA, and reduce the activity of lymphokine in a dose-dependent manner[3].
    Acetylspiramycin (50-200 mg/kg/day; Oral gavage (p.o.); 14 days) in CBA/H mouse models can increase the efficiency of phagocytosis in mice[4].

    Animal Model:CBA/H mice
    Dosage:25-200 mg/kg/day
    Administration:Oral gavage (p.o.), 7 days
    Result:Decreased lymphokine activity in a dose-dependent manner
    Animal Model:CBA/H mice[4]
    Dosage:50-200 mg/kg/day
    Administration:Oral gavage (p.o.), 14 days
    Result:Increased the efficiency of phagocytosis in mice.
  • IC 50 Macrolide
Acetylspiramycin Preparation Products And Raw materials
Raw materials
Preparation Products
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Acetylspiramycin Spectrum
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  • C45H76N2O15
  • 乙酰螺旋霉素,10 MM DMSO 溶液
  • 螺旋霉素杂质10(螺旋霉素II.乙酰螺旋霉素)
  • 乙酰螺旋霉素对照品
  • (4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-二羟基-4,6-二甲基四氢-2H-吡喃-2-基)氧基)-4-(二甲基氨基)-3-羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-10-(((2R,5S,6R)-5-(二甲基氨基)-6-甲基四氢-2H-吡喃-2-基)氧基)-5-甲氧基-9,16-二甲基-2-氧代-7-(2-氧代乙基)氧杂环十六烷-11,13-二烯-4-基 乙酸酯
  • 乙酰螺旋霉素(标准品)
  • 乙酰螺旋霉素
  • 24916-51-6
  • Acetylspiramycin - Mixture of components
  • Acetylspiramycin, 10 mM in DMSO
  • Spiramycin Impurity 10(Spiramycin I)
  • spiramycin ii
  • Acetyl spiramycinQ: What is Acetyl spiramycin Q: What is the CAS Number of Acetyl spiramycin Q: What is the storage condition of Acetyl spiramycin
  • (4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2R,5S,6R)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl acetate
  • Acetylspiramycin USP/EP/BP
  • Spiramycin B, Spiramycin II, Foromacidin B
  • Acetyl helix
  • Acetylspiramycin (ASPM)
  • Spiramycin II (6CI)
  • Spiramycin B (7CI, 8CI)
  • Leucomycin V, 9-O-[5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate, [9(2R,5S,6R)]-
  • Leucomycin V, 9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate
  • Acetyl SpiraMycin (Contains Monoacetyl, Diacetyl and Triacetyl)
  • C12891
  • 9-O-[(2R,5S,6R)-5-Dimethylaminotetrahydro-6-methyl-2H-pyran-2-yl]leucomycin V 3-acetate
  • ACETYLSPIRAMYCIN
  • spiramycinb
  • spiramycin2
  • foromacidineb
  • foromacidinb
  • 9-o-(5-(dimethylamino)tetrahydro-6-methyl-2h-pyran-2-yl)-leucomycin3-ac
  • 9-O-[(2R,5S,6R)-5-(Dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-3-acetate-leucomycin V

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