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Cholesteryl hemisuccinate

Cholesteryl hemisuccinate Structure
Cholesteryl hemisuccinate
  • CAS No.1510-21-0
  • Chemical Name:Cholesteryl hemisuccinate
  • CBNumber:CB0336321
  • Molecular Formula:C31H50O4
  • Formula Weight:486.73
  • MOL File:1510-21-0.mol
Cholesteryl hemisuccinate Property
  • Melting point 178 °C
  • Boiling point 586.0±43.0 °C(Predicted)
  • Density 1.06±0.1 g/cm3(Predicted)
  • refractive index -34 ° (C=2, CHCl3)
  • storage temp. -20°C
  • solubility Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
  • form Solid
  • pka 4.40±0.17(Predicted)
  • color White to Off-White
  • InChIKey WLNARFZDISHUGS-BLYFUZNHSA-N
  • LogP 10.708 (est)
  • CAS DataBase Reference 1510-21-0(CAS DataBase Reference)
  • FDA UNII T3J4KS4201
  • UNSPSC Code 12352103
  • NACRES NA.25
Safety
  • WGK Germany  :3
  • HS Code  :29171900
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Cholesteryl hemisuccinate Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: C6512
  • Product name : Cholesteryl hemisuccinate
  • Purity: 
  • Packaging: 5G
  • Price: ₹18478.28
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: C6512
  • Product name : Cholesteryl hemisuccinate
  • Purity: 
  • Packaging: 25G
  • Price: ₹42553.08
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: C0674
  • Product name : Cholesterol Hydrogen Succinate
  • Purity: 
  • Packaging: 10G
  • Price: ₹16000
  • Updated: 2022/05/26
  • Buy: Buy

Cholesteryl hemisuccinate Chemical Properties,Usage,Production

  • Description Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity. It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively. Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes. It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.
  • Uses Cholesteryl Hemisuccinate is an oxidation product of polyunsaturated fatty acid of cholesterol that alters lysosome structure and functions and induces proinflammatory cytokine production in macrophages.
  • Definition ChEBI: Cholesteryl hemisuccinate is a dicarboxylic acid monoester resulting from the formal condensation of the hydroxy group of cholesterol with one of the carboxy groups of succinic acid. A detergent that is often used to replace cholesterol in protein crystallography, biochemical studies of proteins, and pharmacology. It has a role as a detergent. It is a cholestane ester, a dicarboxylic acid monoester and a hemisuccinate. It is functionally related to a cholesterol.
  • General Description Cholesteryl hemisuccinate (CHEMS) is an acidic cholesterol ester.
  • Biochem/physiol Actions CHEMS can help to maintain the stability of dioleoylphosphatidylethanolamine (DOPE). This amphipathic lipid is used in mixtures with dioleoylphosphatidylethanolamine (DOPE) to form ′pH sensitive′ fusogenic vesicles. It can control cell growth.
Cholesteryl hemisuccinate Preparation Products And Raw materials
Raw materials
Preparation Products
Cholesteryl hemisuccinate Suppliers
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Cholesteryl hemisuccinate Spectrum
1510-21-0, Cholesteryl hemisuccinateRelated Search:
  • Liquid Crystals & Related Compounds
  • Functional Materials
  • Cholesteryl Compounds (Liquid Crystals)
  • 生物化工-提取物
  • 电子材料
  • 化工原料
  • 合成
  • C31H50O4
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  • 1510-21-0
  • 3β-Hydroxy-5-Cholestene 3-Hemisuccinate
  • 5-CHOLESTEN-3β-OL HEMISUCCINATE
  • 6-Amino-2,4-dichloro-26-methylphenol&hydrochloride
  • CHOLESTERYL HYDROGEN SUCCINATE
  • Cholesterol Succinate
  • Cholest-5-en-3-ol (3β)-, 3-(hydrogen butanedioate)
  • Cholesterol Hydrogen Succinate &gt
  • CHOLESTERYL HEMISUCCINATE
  • cholest-5-en-3beta-yl hydrogen succinate
  • Cholesteryl hydrogen succinate Cholesteryl hemisuccinate
  • cholesteryl hemisuccinate free acid
  • cholesterylsuccinate
  • MONO-CHOLESTERYL-SUCCINATE
  • SUCCINIC ACID MONOCHOLESTEROL ESTER
  • 5-CHOLESTEN-3BETA-OL 3-HEMISUCCINATE
  • 5-CHOLESTEN-3-BETA-OL HEMISUCCINATE
  • 5-CHOLESTER-3BETA-YL HYDROGEN SUCCINATE
  • 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE
  • CHOLESTEROL HYDROGEN SUCCINATE
  • Cholest-5-en-3-ol (3b)-, 3-(hydrogen butanedioate)
  • Succinic acid hydrogen cholest-5-en-3β-yl ester
  • Succinic acid hydrogen 3β-cholesteryl ester
  • Succinic acid 1-(3β-cholesteryl) ester
  • Butanedioic acid hydrogen 1-(cholest-5-en-3β-yl) ester
  • 3β-(1,4-Dioxo-4-hydroxybutoxy)cholesta-5-ene

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