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DECYLUBIQUINONE

CAS No.55486-00-5
Chemical Name:DECYLUBIQUINONE
CBNumber:CB0262439
Molecular Formula:C19H30O4
Formula Weight:322.44
MOL File:55486-00-5.mol

DECYLUBIQUINONE Property

Boiling point 452.9±45.0 °C(Predicted)
Density 1.02±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO (up to 10 mg/ml)
form Neat yellow to orange colored oil.
color Yellow or orange
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
FDA UNII DP8EJ59CQN
UNSPSC Code 12162212
NACRES NA.25

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36
WGK Germany :3

NFPA 704:

	3
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H315-H319-H335
Precautionary statements P261-P305+P351+P338

DECYLUBIQUINONE Price More Price(3)

Brand: Sigma-Aldrich(India)
Product number: D7911
Product name : Decylubiquinone
Purity: ≥97% (HPLC)
Packaging: 10MG
Price: ₹8410
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: D7911
Product name : Decylubiquinone
Purity: ≥97% (HPLC)
Packaging: 25MG
Price: ₹17780
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: D7911
Product name : Decylubiquinone
Purity: ≥97% (HPLC)
Packaging: 100MG
Price: ₹48740
Updated: 2022/06/14
Buy: Buy

DECYLUBIQUINONE Chemical Properties,Usage,Production

Description Decylubiquinone (55486-00-5) inhibits the Ca2+?dependent mitochondrial permeability transition pore (MPTP) without inhibiting respiration.1?Maximum effect on Ca2+?retention capacity of rat liver mitochondria at 100 μM. Inhibits etoposide-induced apoptosis in in L929 cells at 5 μM via inhibition of cytochrome C release.2?Delays rotenone-induced cardiac dysfunction in a zebrafish model of development and cardiovascular function.3?Substrate for various quinone oxidoreductases.4,5
Uses Decylubiquinone is inhibits the Ca2+-dependent mitochondrial permeability transition pore (MPTP) and also inhibits etoposide-induced apoptosis.
Definition ChEBI: 6-decylubiquinone is a member of the class of 1,4-benzoquinones that is 2,3-dimethoxybenzoquinone which has been substituted at positions 5 and 6 by decyl and methyl groups. It has a role as a cofactor. It is functionally related to a 6-decylubiquinol.
General Description Ubiquinone analog.
References 1) Fontaine?et al. (1998),?A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore; J. Biol. Chem.,?273?25734 2) Karpinich?et al. (2002),?The course of Etoposide-Induced Apoptosis from Damage to DNA and p53 Activation to Mitochondrial Release of Cytochrome c; J. Biol. Chem.,?277?16547 3) Pinho?et al. (2013)?How mitochondrial dysfunction affects zebrafish development and cardiovascular function: an in vivo model for testing mitochondria-targeted drugs; Br. J. Pharmacol.,?169?1072 4) Kunow?et al.?(1994)?F420H2: quinone oxidoreductase from Archaeoglobus fulgidus. Characterization of a membrane-bound multisubunit complex containing FAD and iron-sulfur clusters; Eur. J. Biochem.,?223?503 5) Zickermann?et al?(1998)?Analysis of the pathogenic human mitochondria mutation ND1/3460 and mutations of strictly conserved residues in it’s vicinity, using the bacterium Paracoccis denitrificans; Biochemistry,?37?11792