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3,5-Dimethoxytoluene

CAS No.4179-19-5
Chemical Name:3,5-Dimethoxytoluene
CBNumber:CB0230254
Molecular Formula:C9H12O2
Formula Weight:152.19
MOL File:4179-19-5.mol

3,5-Dimethoxytoluene Property

Melting point 61-62 C
Boiling point 244 °C (lit.)
Density 1.039 g/mL at 25 °C (lit.)
refractive index n20/D 1.522(lit.)
Flash point 215 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Sparingly)
form Liquid
Specific Gravity 1.039
color Clear colorless to yellow
Odor Warm and sweet, nut-like, earthy-mossy odor
BRN 2043558
LogP 2.897 (est)
CAS DataBase Reference 4179-19-5(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference 3,5-Dimethoxytoluene(4179-19-5)
EPA Substance Registry System 3,5-Dimethoxytoluene (4179-19-5)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36
WGK Germany :3
TSCA :Yes
HS Code :29093090

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338

3,5-Dimethoxytoluene Price More Price(3)

Brand: Sigma-Aldrich(India)
Product number: 423742
Product name : 3,5-Dimethoxytoluene
Purity: 98%
Packaging: 1G
Price: ₹4081.03
Updated: 2022/06/14
Buy: Buy

Brand: TCI Chemicals (India)
Product number: D2526
Product name : 3,5-Dimethoxytoluene
Purity: min. 97.0 %
Packaging: 5G
Price: ₹4700
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: D2526
Product name : 3,5-Dimethoxytoluene
Purity: min. 97.0 %
Packaging: 25G
Price: ₹11800
Updated: 2022/05/26
Buy: Buy

3,5-Dimethoxytoluene Chemical Properties,Usage,Production

Chemical Properties Clear colorless to yellow liquid
Uses 3,5-Dimethoxytoluene (DMT) may be used in the synthesis of 3,5-dimethoxybenzoic acid by oxidation and 2-methoxy-6-methyl-1,4-benzoquinone by catalytic oxidation with hydrogen peroxide (H₂O₂)/methyltrioxorhenium (CH₃ReO₃) in dimethyl carbonate (DMC).
Uses 3,5-Dimethoxytoluene has been suggested for use in perfume compositions as supporting note for Oakmoss and Vetiver, and as a novel note in Chypre, Fougere and Oriental fragrance types.
Definition ChEBI: 3,5-dimethoxytoluene is a member of the class of toluenes that is toluene in which the hydrogens at positions 3 and 5 have been replaced by methoxy groups. It is the major scent compound of many rose varieties. It has a role as a fragrance and a plant metabolite. It is a member of toluenes and a member of methoxybenzenes.
Production Methods 3,5-Dimethoxytoluene can be produced from Orcinol in weak aqueous alkali with Dimethylsulfate at controlled temperature.
Synthesis Reference(s) Organic Syntheses, Coll. Vol. 6, p. 859, 1988
The Journal of Organic Chemistry, 70, p. 3275, 2005 DOI: 10.1021/jo050075r
General Description 3,5-Dimethoxytoluene (DMT) is a methoxylated phenolic derivative. It is reported to be one of the main constituent of the floral volatiles in different rose varieties. It has been biosynthesized from orcinol by two successive methylation catalyzed by O-methyltransferases (OMTs). The features of its aerobic oxidation with metal/bromide catalysts have been investigated.
Synthesis A solution of dry orcinol (14.2 g,0.115 mole) in dry anhydrous acetone(150 ml) containing anhydrous potassium carbonate (45 g) is refluxed withdimethyl sulphate (23.6 ml，31.46 g, 0.25 mole) for 4 hr. The dimethylsulphate is added in small lots of 5 ml. After refluxing, the solution isfiltered and the inorganic residue washed with hot acetone (2 x 25 ml).The combined acetone solution is distilled and the residue macerated withcrushed ice. It is extracted with ether, the ether extract dried (anhydroussodium sulphate) and distilled. Yield 14.2 g (81.6%).B.p.102° (8 mm)