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FENOBAM

FENOBAM Structure
FENOBAM
  • CAS No.57653-26-6
  • Chemical Name:FENOBAM
  • CBNumber:CB0155115
  • Molecular Formula:C11H11ClN4O2
  • Formula Weight:266.68
  • MOL File:57653-26-6.mol
FENOBAM Property
  • Density 1.47±0.1 g/cm3(Predicted)
  • storage temp. Store at RT
  • solubility DMSO: >20mg/mL
  • form solid
  • pka 8.32±0.20(Predicted)
  • color white
  • FDA UNII 078RCY7I27
  • UNSPSC Code 12352202
  • NACRES NA.77
Safety
  • Hazard Codes  :T
  • Risk Statements  :25
  • Safety Statements  :45
  • RIDADR  :UN 2811 6.1 / PGIII
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H300-H315-H319-H335
  • Precautionary statements P233-P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
FENOBAM Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: F0430
  • Product name : Fenobam
  • Purity: ≥98% (HPLC), solid
  • Packaging: 5MG
  • Price: ₹9861.58
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: F0430
  • Product name : Fenobam
  • Purity: ≥98% (HPLC), solid
  • Packaging: 25MG
  • Price: ₹44263.43
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 5.04684
  • Product name : Fenobam - CAS 57653-26-6 - Calbiochem
  • Purity: 
  • Packaging: 5MG
  • Price: ₹13510
  • Updated: 2022/06/14
  • Buy: Buy

FENOBAM Chemical Properties,Usage,Production

  • Uses Sedative-hypnotic.
  • Uses Fenobam is a potent and selective non-competitive mGluR5 antagonist.
  • Biological Activity Primary Target
    mGlu6 receptors', 'Target Ki: 54 nM and 31 nM at recombinant mGlu6 receptors of r at and human, respectively
  • in vivo

    Fenobam (30-60 mg/kg; p.o.; 3 times a week) significantly inhibits self-administration behavior in rats[3].

    Animal Model:Male Long-Evans rats (250-300 g)[3].
    Dosage:30-60 mg/kg
    Administration:Oral administration; 3 times a week.
    Result:Inhibited self-administration.
  • IC 50 mGluR5: 84 nM (IC50); rat mGluR5: 54 nM (Kd); human mGluR5: 31 nM (Kd)
  • storage Room temperature
FENOBAM Preparation Products And Raw materials
Raw materials
Preparation Products
FENOBAM Suppliers
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FENOBAM Spectrum
57653-26-6, FENOBAMRelated Search:
  • Glutamate
  • Glutamate receptor
  • 抑制剂
  • 合成有机化合物配体
  • C11H11N4O2Cl
  • C11H11ClN4O2
  • 非诺班,10 MM DMSO 溶液
  • 1-(3-氯苯基)-3-(1-甲基-4-氧代-4,5-二氢-1H-咪唑-2-基)脲
  • FENOBAM,MGLU 5拮抗剂
  • 非诺班
  • 苯脲咪唑酮
  • 57653-26-6
  • 1-(3-chlorophenyl)-3-(3-methyl-5-oxo-4H-imidazol-2-yl)urea
  • Fenobam, 10 mM in DMSO
  • Fenobam, mGlu5 antagonist
  • 1-(3-Chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea
  • Fenobam,anxiolytic,brain-penetrant,mGluR,nonbenzodiazepine,Inhibitor,addiction,inhibit,cocaine,Metabotropic glutamate receptors
  • Urea, N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)-
  • N-(3-CHLOROPHENYL)-N'-(4,5-DIHYDRO-1-METHYL-4-OXO-1H-IMIDAZOLE-2-YL)UREA
  • N-(3-CHLOROPHENYL)-N'-(4,5-DIHYDRO-1-METHYL-4-OXO-1H-IMIDAZOL-2-YL)UREA
  • Mcn-3377
  • 1-(3-Chlorophenyl)-3-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea
  • FENOBAM

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