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inulicin

inulicin Structure
inulicin
  • CAS No.33627-41-7
  • Chemical Name:inulicin
  • CBNumber:CB01361911
  • Molecular Formula:C17H24O5
  • Formula Weight:308.37
  • MOL File:33627-41-7.mol
inulicin Property
  • Melting point 124.0-126.1 °C
  • Boiling point 481.7±45.0 °C(Predicted)
  • Density 1.16
  • storage temp. 4°C, protect from light
  • solubility DMSO: soluble
  • form A solid
  • pka 13.71±0.60(Predicted)
  • color White to off-white
  • biological source plant
  • UNSPSC Code 12352205
  • NACRES NA.25
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

inulicin Chemical Properties,Usage,Production

  • Uses Inulicin is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
  • Biological Activity Inulicin (1-O-Acetylbritannilactone) is an active compound isolated from Inula Britannica L. It inhibits VEGF-mediated activation of Src and FAK. It also inhibits LPS-induced PGE2 production and COX-2 expression, as well as NF-κB activation and translocation.
  • in vivo Administration of a single dose of Inulicin (1-O-Acetylbritannilactone; 12 mg/kg/day) remarkably suppresses growth of A549 xenografts in nude mice. In vivo microvessels formation and Src activation are also significantly inhibited in Inulicin-treated xenograft tumors. To investigate the potential activity of Inulicin in vivo, a nude mice xenograft model is applied.
  • target

    NF-κB

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    COX-2

  • IC 50 NF-κB; COX-2
inulicin Preparation Products And Raw materials
Raw materials
Preparation Products
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inulicin Spectrum
33627-41-7, inulicinRelated Search:
  • 化合物
  • 倍半萜
  • 对照品-中药对照品
  • 分析试剂标准品
  • 标准品 -中药标准品
  • 标准品
  • 中草药成分
  • 中药对照品
  • 植物提取物
  • 对照品
  • (S)-4-((3AS,4S,7AR)-4-羟基-6-甲基-3-亚甲基-2-氧代-2,3,3A,4,7,7A-六氢苯并呋喃-5-基)戊基 乙酸酯
  • 乙酰旋覆花内酯/1-氧-乙酰旋覆花内酯/1-0-去乙酰旋罗覆花内酯
  • 旋复花内酯,乙酰旋覆花内酯
  • 1-0-去乙酰旋罗覆花内酯
  • 1-O-乙酰基大花旋覆花内酯
  • 乙酰旋覆花内酯
  • 旋覆花素
  • 旋复花内酯
  • 旋覆花内酯
  • 旋覆花次内酯
  • 33627-41-7
  • Inulicin, 10 mM in DMSO
  • (S)-4-((3aS,4S,7aR)-4-Hydroxy-6-methyl-3-methylene-2-oxo-2,3,3a,4,7,7a-hexahydrobenzofuran-5-yl)pentyl acetate
  • inulicin USP/EP/BP
  • Inulicin(1-O-acetyl Britannilactone)
  • 2(3H)-Benzofuranone,5-[(1S)-4-(acetyloxy)-1-methylbutyl]-3a,4,7,7a-tetrahydro-4-hydroxy-6-methyl-3-methylene-,(3aS,4S,7aR)-
  • 1-O-Acetylbritannilactone (Inulicin)
  • 6-(3-acetoxy-propyl)-4-hydroxy-5,7-dimethyl-3-methylene-3,3a,4,5,8,8a-hexahydro-cyclohepta[b]furan-2-one
  • inulicin
  • (3aS,4S,7aR)-5-[(1S)-4-(Acetyloxy)-1-methylbutyl]-3a,4,7,7a-tetrahydro-4-hydroxy-6-methyl-3-methylene-2(3H)-benzofuranone
  • Britannilactone
  • (3aS)-6-(3-Acetoxypropyl)-3,3aα,4,5,8,8aα-hexahydro-4α-hydroxy-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one
  • (3aS)-3,3aα,4,5,8,8aα-Hexahydro-4α-hydroxy-6-(3-acetoxypropyl)-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one