Uses
(±)-Methoxyverapamil hydrochloride has been used:
- as calcium channel antagonist in Schistosoma mansoni parasite
- as calcium entry blocker in cultured macrophages
- in the inhibition of L-type voltage gated Ca2+-channels
Definition
ChEBI: Gallopamil is a member of benzenes and an organic amino compound.
General Description
Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function.
Biochem/physiol Actions
Blocks L-type Ca2+ channels
Side effects
Gallopamil has a distinctly stronger effect
than verapamil but a similar activity profile ,
.
