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Ryanodine

Ryanodine Structure
Ryanodine
  • CAS No.15662-33-6
  • Chemical Name:Ryanodine
  • CBNumber:CB1480087
  • Molecular Formula:C25H35NO9
  • Formula Weight:493.55
  • MOL File:15662-33-6.mol
Ryanodine Property
  • alpha  :D25 +26° (methanol)
  • Boiling point: :586.95°C (rough estimate)
  • Density  :1.2805 (rough estimate)
  • refractive index  :1.6000 (estimate)
  • storage temp.  :Sealed in dry,2-8°C
  • solubility  :DMSO: soluble10mg/mL, clear
  • form  :White solid
  • Melting point: :219-220 °C
  • pka :10.66±0.70(Predicted)
  • color  :white to beige
  • CAS DataBase Reference :15662-33-6
  • FDA UNII :37H6ATE4SA
  • EPA Substance Registry System :Ryanodine (15662-33-6)
Safety
  • Hazard Codes  :Xn,N
  • Risk Statements  :21/22-50/53
  • Safety Statements  :36/37-60-61
  • RIDADR  :UN 3077 9/PG 3
  • RTECS  :VM4025000
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302+H312-H410
  • Precautionary statements P273-P280-P501
Ryanodine Price More Price(2)
  • Brand: Sigma-Aldrich
  • Product number: 559276
  • Product name : Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem
  • Purity: Naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum.
  • Packaging: 500 μg
  • Price: $205.35
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 559276
  • Product name : Ryanodine, High Purity
  • Purity: 
  • Packaging: 500ug
  • Price: $214
  • Updated: 2020/08/18
  • Buy: Buy

Ryanodine Chemical Properties,Usage,Production

  • Description Ryania insecticide is the ground stem wood of the tropical tree Ryania speciosa Vahl., and it contains over a dozen of several structurally related alkaloids. Nowadays, this botanical preparation is of minor importance, but one of its major ingredients, ryanodine, is a widely used pharmacological tool in studies of the calcium release channels in sarcoplasmic reticulum membranes of skeletal and cardiac muscle of both insects and mammals (11,12).
  • Chemical Properties white to off-white solid
  • Uses Insecticide.
  • Definition ChEBI: An insecticide alkaloid isolated from South American plant Ryania speciosa.
  • Biological Activity Potent inhibitor of Ca 2+ release from sarcoplasmic reticulum (IC 50 values are 10 and 2.8 nM in skeletal and cardiac muscle respectively).
  • References Rogers et ai., J. Amer. Chem. Soc., 70, 3086 (1948)
    Kelly, Whittingham, Wusner., Chem. Ind., 857 (1952)
    Structure:
    Wiesner, Valenta, Findlay., Tetrahedron Lett., 221 (1967)
    Hollstein, Rapoport.,J. Amer. Chem. Soc., 90,3864 (1968)
    Wong, Hollstein, Rapoport., ibid, 90, 3866 (1968)
    Wiesner., Collect. Czech. Chem. Commun., 33, 2656 (1968)
    Crystal structure:
    Srivastava, Przybylska., Can. J. Chem., 46,795 (1968)
Ryanodine Preparation Products And Raw materials
Raw materials
Preparation Products
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15662-33-6, RyanodineRelated Search:
  • Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem
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  • 6-(1α,5aβ,8aβ,9-pentahydroxy-7β-isopropyl-2β,5β,8β-trimethylperhydro-8bα,9-epoxy-5,8-ethanocyclopenta[1,2-b]indenyl) pyrrole-2-carboxylate ryania
  • Ryanodine from Ryania speciosa
  • Ryanodol 3-(1H-pyrrole-2-carboxylate) from Ryania speciosa
  • RYANODINE MIXTURE
  • RYANADOL
  • RYANADOL 3-(1H-PYRROLE-2-CARBOXYLATE)
  • Ryania(content>30%)
  • Ryanicide
  • RYANODINE
  • RYANODOL-3-(1H-PYRROLE-2-CARBOXYLATE)
  • 1H-PYRROLE-2-CARBOXYLIC ACID, (3S,4R,4AR,6S,7S,8R,8AS,8BR,9S,9AS)-DODECAHYDRO-4,6,7,8A,8B,9A-HEXAHYDROXY-3,6A,9-TRIMETHYL-7-(1-METHYLETHYL)-6,9-METHANOBENZO[1,2]PENTALENO[1,6-BC]FURAN-8-YL ESTER
  • 3-(1H-PYR-ROLE-2-CARBOXYLATE)
  • bonideryatox
  • groundryaniaspecisa(vahl)stemwood(alkoloidryanodine)
  • ryanexel
  • 1H-Pyrrole-2-carboxylic acid, (3S,4R,4aR,6S,6aS,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-yl ester
  • ryania
  • ryaniapowder
  • ryaniaspeciosa
  • ryanodinealkaloid
  • 6-(1alpha,5abeta,8abeta,9-pentahydroxy-7beta-isopropyl-2beta,5beta,8beta-trimethylperhydro-8balpha,9-epoxy-5,8-ethanocyclopenta[1,2-b]indenyl) pyrrole-2-carboxylate
  • RYANODINE >98% (RYANADOL, 3-(1H-PYRR
  • RYANODINE FROM RYANIA SPECIOSA MINIMUM &
  • RYANODINE FROM RYANIA SPECIOSA INHIBITS CALCIUM RELEASE FROM THE SARCOPLASMIC RETICULUM
  • RYANODINE FROM RYANIA SPECIOSA A MIXTURE OF RYANODINE AND 9,21-DEHYDRORYANODINE (1:1)
  • RYANODINE HIGH PURITY
  • 1H-Pyrrole-2-carboxylicacid(3S,4R,4aR,6S,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethy]
  • 9,21-DEHYDRO(RG)
  • 15662-33-6
  • C25H35NO9
  • Signalling
  • Alkaloids
  • InsP3/Ryanodine receptor