Chemical Properties
All isomers have a characteristic odor.
Chemical Properties
off-white to light tan crystals or powder
Uses
Biocide; disinfectant for home, hospital and farm.
Uses
It is used as main raw material of compounding for medicine, dye, plastic and other industries. 4-Chlorophenol was used in visible-light-induced degradation of 4-chlorophenol in aqueous suspension of pure TiO2.
Uses
Intermediates of Liquid Crystals
Definition
ChEBI: A monochlorophenol substituted at the pare position by a chlorine atom.
General Description
White crystals with a strong phenol odor Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible. Used as an intermediate in organic synthesis of dyes and drugs.
Air & Water Reactions
Slightly soluble to soluble in water.
Reactivity Profile
CHLOROPHENOLS, SOLID are incompatible with acid chlorides, acid anhydrides and oxidizing agents. Also incompatible with iron . Liquefy and darken in color at temperatures above 108°F.
Hazard
Toxic by skin absorption, inhalation, or
ingestion; strong irritant to tissue.
Health Hazard
Inhalation causes headache, dizziness, weak pulse. Ingestion causes irritation of mouth and stomach; headache, dizziness, weak pulse. Contact with eyes causes severe irritation and burning. Contact with skin causes irritation and burn; if absorbed, causes same symptoms as inhalation.
Fire Hazard
Special Hazards of Combustion Products: Toxic and irritating hydrogen chloride and chlorine gases may form in fires.
Flammability and Explosibility
Not classified
Safety Profile
Poison by inhalation
and intraperitoneal routes. Moderately toxic
by ingestion, skin contact, and subcutaneous
routes. A severe skin and eye irritant.
Human systemic effects by inhalation:
excitement, irritability. Mutation data
reported. Combustible when exposed to
heat or flame. To fight fire, use water, spray,
mist, fog, foam, dry chemical. When heated
to decomposition it emits toxic fumes of
Cl-. See also CHLOROPHENOLS and
CHLORIDES.
Potential Exposure
Monochlorophenols are used in the
manufacture of fungicides, slimicides, bactericides, pesticides, herbicides, disinfectants, wood and glue preservatives; in the production of phenolic resins; in the extraction
of certain minerals from coal; as a denaturant for ethanol;
as an antiseptic; as a disinfectant, and others.
Shipping
UN 2020 (solid); UN2021 (liquid) Chlorophenols, solid and liquid, Hazard Class: 6.1; Labels:
6.1-Poisonous materials.
Purification Methods
Distil the phenol, then crystallise it from pet ether (b 40-60o) or hexane, and dry it under vacuum over P2O5 at room temperature. [Bernasconi & Paschalis J Am Chem Soc 108 2969 1986, Beilstein 6 IV 820.]
Incompatibilities
May form explosive mixture with air.
Contact with oxidizing agents can cause fire and explosion
hazard. Heat produces hydrogen chloride and chlorine.
Corrosive to aluminum, copper and other chemically active
metals.
Waste Disposal
Incinerate in admixture with
flammable solvent in furnace equipped with afterburner
and scrubber.
