Chemical Properties
white or off-white powder or crystals
Originator
4-Acetamidobenzoic acid ,ARIAC
Uses
Acedoben is the acetylated derivative of p-aminobenzoic acid (PABA). Acedoben is a metabolite of the anesthetic Benzocaine (B202970).
Uses
immune stimulant (component)
Definition
ChEBI: A amidobenzoic acid that consists of benzoic acid bearing an acetamido substituent at position 4.
Manufacturing Process
Into a 2 L, 3-necked flask set in a tub and equipped with a stirrer, an air
condenser (drying tube), thermometer, was placed 860 ml of water, 43.0 g of
MgSO4 and 43.0 g of sodium acetate and heated on water bath. Into heated
solution to 70°C stirring 43.0 g of N-p-tolylacetamide were added. Then 136.0
g of KMnO4 by small portions were added at 75°-80°C. The reaction mixture
allow to stand for 6 h and stirring was continue till the solution became
colorless. Hot solution was filtered and filtrate treated hydrochloric acid to
slightly acidic pH. After that 44.0 g (85%) of p-acetoaminobenzoic acid was
obtained as white precipitate, melting point 250°C.
Therapeutic Function
Antiviral
General Description
Needles or off-white powder.
Air & Water Reactions
Water insoluble.
Reactivity Profile
Simultaneously an amide and a carboxylic acid.
Fire Hazard
Flash point data for p-Acetylamino benzoic acid are not available; however, p-Acetylamino benzoic acid is probably combustible.
