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SR-95531

SR-95531 Structure
SR-95531
  • CAS No.104104-50-9
  • Chemical Name:SR-95531
  • CBNumber:CB9356638
  • Molecular Formula:C15H18BrN3O3
  • Formula Weight:368.23
  • MOL File:104104-50-9.mol
SR-95531 Property
  • Melting point: :200 °C(Solv: ethanol (64-17-5))
  • storage temp.  :Store at RT
  • solubility  :DMSO: 30 mg/mL
  • form  :solid
  • color  :white
  • EWG's Food Scores :1
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
SR-95531 Price More Price(22)
  • Brand: Sigma-Aldrich
  • Product number: 5.05986
  • Product name : SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem
  • Purity: 
  • Packaging: 10 mg
  • Price: $129
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: S106
  • Product name : SR-95531
  • Purity:  ≥98% (HPLC), powder
  • Packaging: 50mg
  • Price: $539
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 5.05986
  • Product name : SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem
  • Purity: 
  • Packaging: 5059860001
  • Price: $124
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 14585
  • Product name : SR 95531 (hydrobromide)
  • Purity: ≥98%
  • Packaging: 10mg
  • Price: $94
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 14585
  • Product name : SR 95531 (hydrobromide)
  • Purity: ≥98%
  • Packaging: 5mg
  • Price: $59
  • Updated: 2021/12/16
  • Buy: Buy

SR-95531 Chemical Properties,Usage,Production

  • Description SR 95531 is a derivative of γ-aminobutyric acid (GABA) that acts as an antagonist of GABAA receptors (Ki = 74-150 nM). When administered intravenously, it elicits seizures in mice. SR 95531 differs in action from bicuculline (Item No. 11727) in that it antagonizes GABA-induced chloride currents but not those induced by pentobarbitone. It is effective against GABAA receptor isoforms from mice, rats, and humans.
  • Uses Gabazine Hydrobromide is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites.
  • Biological Activity Selective, competitive GABA A receptor antagonist. Displaces [ 3 H]-GABA from rat brain membranes with a K i of 150 nM. Unlike bicuculline, selectively antagonizes GABA-induced Cl - currents with little action on pentobarbitone-induced currents. Also acts as a low affinity glycine receptor antagonist.
  • Biochem/physiol Actions SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities.
SR-95531 Preparation Products And Raw materials
Raw materials
Preparation Products
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104104-50-9, SR-95531Related Search:
  • Gabazine, 2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromide
  • 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, monohydrobromide
  • 6-Amino-5-methyl-3-(4-methoxyphenyl)-1-pyridaziniumbutyric acid br
  • 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid monohydrobromide
  • Gabazine Hydrobromide
  • 4-(6-Imino-3-(4-methoxyphenyl)pyridazin-1(6H)-yl)butanoic acid hydrobromide
  • GABAZINE
  • GABAZINE BROMIDE
  • 2-(3-CARBOXYPROPYL)-3-AMINO-6-(4-METHOXYPHENYL)PYRIDAZINIUM
  • 2-(3-CARBOXYPROPYL)-3-AMINO-6-(4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE
  • 6-IMINO-3-(4-METHOXYPHENYL)-1(6H)-PYRIDAZINEBUTANOIC ACID HYDROBROMIDE
  • SR 95531 HYDROBROMIDE
  • SR-95531
  • SR 95531 hydrobromide NEW
  • SR 95531 hydrobromid
  • 104104-50-9
  • 104105-50-9
  • C15H17N3O3HBr
  • C15H18BrN3O3
  • C15H18N3O3Br
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Ion Channels
  • Ligand-Gated Ion Channels
  • GABA and Glycine Receptor Modulators
  • GABA/Glycine receptor