4-(Trimethylsilyl)ethynylbenzaldehyde

Uses

4-?(Trimethylsilyl)?ethynylbenzaldehyde is a useful reactant for the synthesis of acetylene-?substituted naphthalene diimides in polar solvents.

General Description

4-[(Trimethylsilyl)ethynyl]benzaldehyde can be synthesized by reacting 4-bromobenzaldehyde and triphenylphosphine in anhydrous triethylamine with ethynyltrimethylsilane and then with palladium(II) acetate under argon. It can also be prepared by Sonogashira coupling reaction between 4-bromobenzaldehyde and (trimethylsilyl) ethynyl.