Description
Iopromide is a non-ionic, water-soluble X-ray contrast agent for intravascular administration. Iopromide can cause acute kidney injury and is used in animal models of contrast-induced nephropathy.
Chemical Properties
White Solid
Uses
Labelled Iopromide. Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).
Definition
ChEBI: A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A
ater soluble x-ray contrast agent for intravascular administration.
brand name
Ultravist (Berlex).
General Description
Iopromide is a low-osmolar,nonionic monomer with 48% bound iodine content. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.
Side effects
Most common adverse reactions (>1%) are headache, nausea, injection site and infusion site reactions, vasodilatation, vomiting, back pain, urinary urgency, chest pain, pain, dysgeusia, and abnormal vision.
References
[1] YOUNG-HWAN AHN. The potential utility of iodinated contrast media (ICM) skin testing in patients with ICM hypersensitivity.[J]. Journal of Korean Medical Science, 2015, 30 3: 245-251. DOI:
10.3346/jkms.2015.30.3.245[2] JIN-YONG PARK. A new micro-computed tomography-based high-resolution blood-brain barrier imaging technique to study ischemic stroke.[J]. Stroke, 2014, 45 8: 2480-2484. DOI:
10.1161/strokeaha.114.006297[3] KAMAL HASSAN Hassan F. Is hypoalbuminemia a prognostic risk factor for contrast-induced nephropathy in peritoneal dialysis patients[J]. Therapeutics and Clinical Risk Management, 2014, 10: 787-795. DOI:
10.2147/tcrm.s70665[4] NA WANG. Renal Protective Effect of Probucol in Rats with Contrast-Induced Nephropathy and its Underlying Mechanism.[J]. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 2015: 2886-2892. DOI:
10.12659/msm.895543
