Divaplon

Uses

Divaplon is a GABA receptor agonist with the EC50 values of 31 and 2 nM for α3β2γ2 and α5β2γ2, respectively. Divaplon shows anxiolytic activity[1][2].

References

[1] Knoflach F, et al. Full and partial agonism displayed by benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes. J Pharmacol Exp Ther. 1993;266(1):385-391. PMID:8392559
[2] Sanger DJ, et al. Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice. Psychopharmacology (Berl). 1995;121(1):104-108. DOI:10.1007/BF02245596