Description
Toloxatone is a selective, reversible and competitive inhibitor of type A
monoamine oxidase (MAO-A) which shows clinical utility as an antidepressant. It
is reportedly free of the "cheese effect" in man, possibly due to the reversible
nature of its inhibitory effect on intestinal MAO-A in the presence of high
concentrations of tyramine.
Originator
Delalande (France)
Uses
Toloxatone is a monoamine oxidase-A (MAO-A) inhibitor.
Definition
ChEBI: 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one is a member of the class of oxazolidinones that is 5-(hydroxymethyl)-1,3-oxazolidin-2-one substituted by a 3-methylphenyl group at position 3. It is a member of toluenes, an oxazolidinone and a primary alcohol.
