Description
5(S)-
HETrE is produced by the action of 5-
LO when mead acid is the substrate.
1,2 There are no literature reports of the biological activity or further metabolic fate of 5(S)-
HETrE.
Definition
ChEBI: 5(S)-HETrE is a 5-HETrE consisting of (6E,8Z,11Z)-icosatrienoic acid in which the 5-hydroxy group has S-configuration. It has a role as a human xenobiotic metabolite.
References
1. Jakschik, B.A., Sams, A.R., Sprecher, H., et al.
Fatty acid structural requirements for leukotriene biosynthesis Prostaglandins 20,401-410(1980).
2. Jakschik, B.A., Morrison, A.R., and Sprecher, H.
Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway J. Biol. Chem. 258,12797-12800(1983).