Chemical Properties
Colorless to light yellow liqui
Uses
1-Bromo-3-phenylpropane is used in the synthesis of MraY natural inhibitors as antibacterial agents. Also used in the preparation of quinolinone derivatives as potent and selective MAO-B inhibitors.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 31, p. 4189, 1983
DOI: 10.1248/cpb.31.4189
Purification Methods
Wash the bromide successively with conc H2SO4, water, 10% aqueous Na2CO3 and again with water, then dry it with CaCl2 and fractionally distil it just before use. [Beilstein 5 IV 982.]