Uses
4’-Hydroxy-3’,5’-dimethoxyacetophenone used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents. It is a naturally occuring compound found in plants and used in plant-pathogen recognition.
Description
Acetosyringone is a phenol secreted by wounded plant tissues. It induces expression of virulence A genes and chemotaxis in
A. tumefaciens strains that contain a tumor-inducing plasmid used to transfer genetic information to plant cells. Acetosyringone is widely used to increase efficacy of genetic transformation for the creation of genetically modified dicotyledonous and monocotyledonous plants.
Chemical Properties
beige to light brown crystalline powder
Uses
A buffer also known as acetosyringone that is used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents in vitro.
Uses
4’-Hydroxy-3’,5’-dimethoxyacetophenone used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents. It is a naturally occuring compound found in plants and used in plant-pathogen recognition.
Uses
insect attractant, plant hormone
Preparation
Preparation by adding a solution of 4-hydroxy-3- iodo-5-methoxyacetophenone and cupric chloride in DMF to a solution of sodium methoxide in methanol and heating between 105° and 120° (86%).
Definition
ChEBI: A member of the class of acetophenones that is 1-phenylethanone substituted by a hydroxy group at position 4 and methoxy groups at positions 3 and 5.
References
[1] SHAW C H. Swimming against the tide: Chemotaxis in Agrobacterium[J]. BioEssays, 1991, 13 1: 25-29. DOI:
10.1002/bies.950130105[2] YONG-WOOG LEE . The sensing of plant signal molecules by Agrobacterium: genetic evidence for direct recognition of phenolic inducers by the VirA protein[J]. Gene, 1996, 179 1: Pages 83-88. DOI:
10.1016/s0378-1119(96)00328-9[3] RAMACHANDRAN SRINIVASAN Kodiveri M G. Synergistic Action of D-Glucose and Acetosyringone on Agrobacterium Strains for Efficient Dunaliella Transformation.[J]. PLoS ONE, 2016: e0158322. DOI:
10.1371/journal.pone.0158322
