Description
The presence of halogen substituents on the fluorescent group improves the membrane permeability of YVAD-derived Caspase-1 substrate Z-YVAD-AFC.
Uses
Z-YVAD-AFC is a fluorescent substrate for Caspase-1, which can be used to detect and measure the activity of Caspase-1[1].
References
[1] Vikas Kaushal, et al. P2-120: Inflammasome-mediated activation of caspase-1 and caspase-6 in primary human neurons. Volume8,Issue4S_Part_8.Alzheimer 's Association International Conference 2012.
Sequene
Cbz-Tyr-Val-Ala-Asp-AFC
