Uses
4-
O-Caffeoylquinic acid has been used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).
Uses
Cryptochlorogenic acid may be used as a reference standard in the determination of cryptochlorogenic acid in the leaves of
Hibiscus sabdariffa using high performance liquid chromatography coupled with mass spectrometry (HPLC-MS).
Definition
ChEBI: A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 4-hydroxy group of (+)-quinic acid.
General Description
Cryptochlorogenic acid is a polyphenol, found in a variety of plants, which plays a crucial role in protection against various age-related diseases.
Biochem/physiol Actions
4-O-Caffeoylquinic acid (4-CQA) is a major active antioxidant marker in mulberry leaf extract. It is an inhibitor of ferroptosis hence, it is recognized as a potent anti-diabetic agent. 4-CQA plays an important role in the upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway.