Chemical Properties
white to slightly yellow low melting solid
Uses
3,4-Dichlorobenzaldehyde was used to design and prepare chalcone derivatives as potential antitumor agents, anti-inflammatory and cancer chemopreventive agents.
General Description
White crystalline solid or chunky powder.
Air & Water Reactions
3,4-Dichlorobenzaldehyde may be sensitive to prolonged exposure to air, light and moisture. Insoluble in water.
Reactivity Profile
3,4-Dichlorobenzaldehyde is incompatible with strong oxidizers and strong bases. 3,4-Dichlorobenzaldehyde may also be incompatible with iron.
Fire Hazard
3,4-Dichlorobenzaldehyde is probably combustible.
Synthesis
3,4-Dichlorobenzaldehyde (10c) was synthesized through a series of reactions using 1,2-dichloro-4-(trichloromethyl)benzene as starting material. The product was characterized by nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 500 MHz, CDCl3) with chemical shifts of δ9.95 (s, 1H), 7.97 (s, 1H), 7.73 (d, 1H, J = 8.0 Hz), 7.64 (d, 1H, J = 8.0 Hz), respectively. The 1H NMR spectra of the obtained products were in agreement with the data reported in reference 20, confirming the structure of the target compounds.
References
[1] Tetrahedron, 2014, vol. 70, # 30, p. 4540 - 4546
