Chemical Properties
white needle-like crystals or powder
Uses
Intermediate in dyes, pharmaceuticals, plasticizers,
and other organic materials; flame-retardant
in epoxy resins.
Uses
Tetrachlorophthalic Anhydride is used in the synthesis of nucleoside analogues with a specific structure as apoptosis inducing active compounds. Also used in the synthesis of carbonic anhydrase inhbitors. Chlorinated Reactive Flame Retardant Intermediate
Definition
ChEBI: A cyclic dicarboxylic anhydride that is phthalic anhydride chlorinated at the 4-, 5-, 6- and 7-positions.
General Description
Odorless needle-like crystals or white powder.
Air & Water Reactions
Sensitive to air and moisture.
Reactivity Profile
4,5,6,7-Tetrachloro-1,3-isobenzofurandione reacts exothermically with water. This reaction is expected to be slow, but can become vigorous if local heating accelerates it. Reaction with water is accelerated by acids. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Fire Hazard
Flash point data for 4,5,6,7-Tetrachloro-1,3-isobenzofurandione are not available. 4,5,6,7-Tetrachloro-1,3-isobenzofurandione is probably combustible.
Flammability and Explosibility
Not classified
Purification Methods
Crystallise the anhydride from chloroform or *benzene, then sublime it in a vacuum. [Beilstein 17/11 V 260.]
