Otelixizumab
- Product NameOtelixizumab
- CAS881191-44-2
- CBNumberCB78080780
- MW0
- MOL FileMol file
- MSDS FileSDS
Otelixizumab Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| ChemScene CS-0612958 | 1mg | $282 | Otelixizumab 99.64% |
Buy |
| ChemScene CS-0612958 | 5mg | $737 | Otelixizumab 99.64% |
Buy |
| ChemScene CS-0612958 | 10mg | $1170 | Otelixizumab 99.64% |
Buy |
| aablocks AA0294RN | 1mg | $480 | Otelixizumab ≥95%(SDS-PAGE&SEC-HPLC) |
Buy |
| aablocks AA0294RN | 5mg | $1600 | Otelixizumab ≥95%(SDS-PAGE&SEC-HPLC) |
Buy |
Otelixizumab Chemical Properties,Usage,Production
Uses
Otelixizumab (ChAglyCD3) is an anti-human CD3 monoclonal antibody and can be used for the research of type 1 diabetes[1].in vivo
Otelixizumab (ChAglyCD3) (100 μg/mouse; i.v.; once) results in durable disease remission dependent on transferable T cell–mediated tolerance in diabetic transgenic mice[1].
| Animal Model: | BALB/c-huCD3e mice carrying the human CD3e chain[1] |
| Dosage: | 100 μg/mouse |
| Administration: | Intravenous injection, once |
| Result: | Induced secretion of lower amounts of IL-6. Exhibited up-regulation of regulatory T cells. |
References
[1] Kuhn C, et al. Human CD3 transgenic mice: preclinical testing of antibodies promoting immune tolerance. Sci Transl Med. 2011 Feb 2;3(68):68ra10. DOI:10.1126/scitranslmed.3001830[2] Guglielmi C, et al. Efficacy and safety of otelixizumab use in new-onset type 1 diabetes mellitus. Expert Opin Biol Ther. 2016 Jun;16(6):841-6. DOI:10.1080/14712598.2016.1180363
Preparation Products And Raw materials
Otelixizumab Suppliers
Global(26)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 9920 | 65 | |
| 18916372613 | yanzihan@shyuanye.com | China | 87240 | 60 | |
| 177-54423994 17754423994 |
2853530910@QQ.com | China | 8000 | 62 | |
| 15817493340 | 981810490@qq.com | China | 1577 | 58 | |
| 027-65317797 15926423062 |
422450190@qq.com | China | 10300 | 58 | |
| 010-60605840 | psaitong@jm-bio.com | China | 27756 | 58 | |
| 4008200310 15002144251 |
marketing@tsbiochem.com | China | 24951 | 58 | |
| 027-65279366 18108604356 |
products@biolabreagent.com | China | 9864 | 58 | |
| 13720134139 086-15871494362 13720134139 |
orders@jknbiochem.com | China | 7284 | 58 | |
| 021-65675885 18964387627 |
customer_service@efebio.com | China | 11963 | 58 |
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