(-)-ISOCARYOPHYLLENE

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(-)-ISOCARYOPHYLLENE Chemical Properties,Usage,Production

• Uses

  Isocaryophyllene is an Z- isomer of β-Caryophyllene (C184725). β-Caryophyllene is one of the chemical compounds that contributes to the spiciness of black pepper. β-Caryophyllene was shown to selectively bind to the cannabinoid receptor type-2 (CB2) and to exert significant cannabimimetic antiinflammatory effects in mice.

• Uses

  In perfumery.

• Purification Methods

  Purify it by vacuum distillation or GLC using a nitrile-silicone column [Corey et al. J Am Chem Soc 86 485 1964, Ramage & Simonsen J Chem Soc 741 1936, Kumar et al.Synthesis 461 1976]. [Beilstein 5 III 1085.]

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