FORTUNELLIN
- Product NameFORTUNELLIN
- CAS20633-93-6
- CBNumberCB7713662
- MFC28H32O14
- MW592.55
- MDL NumberMFCD00063944
- MOL File20633-93-6.mol
Chemical Properties
Melting point | 193-198°C |
Boiling point | 888.7±65.0 °C(Predicted) |
Density | 1.62±0.1 g/cm3(Predicted) |
pka | 6.10±0.40(Predicted) |
FORTUNELLIN Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Biosynth Carbosynth OA71574 | 5mg | $800 | Acacetin-7-neohesperidoside |
Buy |
American Custom Chemicals Corporation CHM0029941 | 5MG | $933.82 | FORTUNELLIN 95.00% |
Buy |
Biosynth Carbosynth OA71574 | 10mg | $1200 | Acacetin-7-neohesperidoside |
Buy |
Biosynth Carbosynth OA71574 | 25mg | $2500 | Acacetin-7-neohesperidoside |
Buy |
Biosynth Carbosynth OA71574 | 1mg | $300 | Acacetin-7-neohesperidoside |
Buy |
FORTUNELLIN Chemical Properties,Usage,Production
Description
Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation.Chemical Properties
Off-white to light yellow SolidUses
Fortunellin is a flavonoid that can be isolated from kumquat (Fortunella margarita) fruit. Studies have shown that Fortunellin inhibits LPS-induced inflammation and ROS production in H9C2 cells, and also prevents fructose-induced inflammation and oxidative stress by enhancing the AMPK/Nrf2 pathway. In addition, Fortunellin has a dual role in the prevention and treatment of coronaviral disease, with antiviral activity against SARS-CoV-2 and anti-inflammatory immunomodulatory capacity in the host.Biological Functions
Fortunellin (acacetin 7-O-neohesperidoside) is a citrus flavonoid isolated from kumquat fruit. Kumquat extract has attracted much attention recently for its beneficial effects on human health, which include antitumor, antioxidant and anti-inflammatory characteristics . The beneficial effects of flavonoids on IBD have been confirmed in many studies. However, although fortunellin is the main flavonoid in kumquat, there is a lack of information on its alleviation of IBD.Mechanism of action
Fortunellin is a citrus flavonoid that is a potential anti-inflammation agent in inflammatory diseases. Fortunellin ameliorated colitis symptoms, including excessive inflammation and oxidative stress. Fortunellin decreased epithelial cell apoptosis through inhibiting PTEN expression in colitis. Fortunellin-induced downregulation of PTEN could be counteracted by miR-374a depletion. Moreover, knockdown of miR-374a in vivo partly inhibited the effects of fortunellin on rat colitis.Preparation Products And Raw materials
Preparation Products
FORTUNELLIN Suppliers
Global(48)Suppliers
Supplier | Tel | Country | ProdList | Advantage | ||
---|---|---|---|---|---|---|
+86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9626 | 58 | ||
+1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 | ||
+1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 | ||
+8613720134139 | orders@jknbiochem.com | China | 4692 | 58 | ||
021-61259108 18621169109 |
market03@meryer.com | China | 40240 | 62 | ||
1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14059 | 65 | ||
021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 | ||
027-87465837 19945049750 |
sales@finetechnology-ind.com | China | 9625 | 58 | ||
18607101326 15172504745 |
aileen@chemfaces.com | China | 7059 | 55 | ||
021-61312847; 18021002903 |
3008007409@qq.com | China | 27322 | 60 |
20633-93-6, FORTUNELLINRelated Search
PROMPT×
PROMPT
The What'sApp is temporarily not supported in mainland China
The What'sApp is temporarily not supported in mainland China
Cancel
Determine