Uses
5(R)-HETE is a lipoxygenase product of arachidonic acid. 5(R)-HETE is an inducer of neutrophil migration through endothelial and epithelial barriers. 5(R)-HETE is important in mediating lung inflammatory processes[1].
Definition
ChEBI: 5R-HETE is a hydroxy fatty acid and a polyunsaturated fatty acid.
References
[1] D B Bittleman, et al. 5-Hydroxyeicosatetraenoic acid (HETE)-induced neutrophil transcellular migration is dependent upon enantiomeric structure. Am J Respir Cell Mol Biol. 1995 Mar;12(3):260-7. DOI:
10.1165/ajrcmb.12.3.7873191