Uses
Malachite Green Carbinol base (MGOH, MGCB) is a derivative of Malachite green (MG) with not fluorescence. Malachite green carbinol base (MGOH, MGCB), as a pH regulation reagent, MGCB molecule could release OH- under UV light irradiation and generate a progressive shift in pH values. MGCB solution turns from colorless to deep green rapidly when exposed to a high-pressure UV lamp (500 W, 50 W/cm)[1][2].
Definition
ChEBI: Malachite Green carbinol is a benzenoid aromatic compound.
Purification Methods
The oxalate [Beilstein 8 H 326, 13 IV 2279.] is recrystallised from hot water and dried in air. The carbinol is precipitated from the oxalate (1g) in distilled water (100mL) by adding M NaOH (10mL). The precipitate is filtered off, recrystallised from 95% EtOH containing a little dissolved KOH, then washed with ether, and crystallised from pet ether. Dry it in a vacuum at 40o. An acid, almost colourless, solution (2 x 10-5M in 6 x 10-5M H2SO4) rapidly reverts to the coloured dye. [Swain & Hedberg J Am Chem Soc 72 3373 1950, Beilstein 13 H 243, 744.]
Properties and Applications
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TEST ITEMS
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SPECIFICATION
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APPEARANCE
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Malachite Green Powder
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SHADE
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Bluish
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HEAT RESISTANCE
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140 °C min
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LIGHT FASTNESS
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4
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ACID RESISTANCE
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4
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ALKALI RESISTANCE
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4
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WATER RESISTANCE
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5
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DENSITY
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1.10g/cm
3
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RESIDUE ON 80 MESH
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5.0% max
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WATER SOLUBLE
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1.0% max
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VOLATITE 105 °C
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1.0% max
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TINTING STRENGTH
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100-105 %
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WEIGHT METAL TOTAL
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50ppm max
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References
[1] Yubin Zhou, et al. Organic additives stabilize RNA aptamer binding of malachite green. Talanta. 2016 Nov 1;160:172-182 DOI:
10.1016/j.talanta.2016.06.067[2] Can Xu, et al. Versatile Dual Photoresponsive System for Precise Control of Chemical Reactions. ACS Nano. 2017 Aug 22;11(8):7770-7780. DOI:
10.1021/acsnano.7b01450
