Uses
2,6-Dihydroxynaphthalene is used in the preparation of 1,5-dichloro-2,6-diethynylnaphthalenes. It is used to produce convulsions in mice. It exhibits antiproliferative activity towards certain cells. It is also employed in the preparation of the first-generation rotaxane dendrimer. Further, it is used in the production of several dyes, pigments, fluorescent whiteners, tanning agents, antioxidants and antiseptics. In addition to this, it is converted into amines, esters, ethers and carboxylic derivatives.
Synthesis
2,6-Naphthalenediol [581-43-1], 2,6- naphthohydroquinone, mp 222℃, is synthesized by potassium hydroxide fusion of 2-hydroxynaphthalene-6-sulfonic acid at 295℃. It undergoes amination at 250℃ to give 2,6-naphthalenediamine and couples with diazotized anilines in the 1-position under acid conditions or the 1,5- positions under alkaline conditions.
