Reaction
Palladium precatalyst for facile C-N cross-coupling reactions.
Uses
Convenient dosable form of XPhos-Pd-G3.
0.025 mmoles per capsule (1EA = 0.025 mmoles)
Uses
XPhos Pd G3 may be used in the following reactions:
- Cyanation reaction of heterocyclic halides.
- Coupling of heteroaryl chlorides with polyfluoroaryl zinc reagents.
- Coupling of 2,6-difluorophenylboronic acid with (hetero)aryl chlorides.
General Description
XPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. XPhos Pd G3 is an excellent reagent for Suzuki cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.