Description
2',3'-Isopropylideneuridine has been shown to inhibit binding of pestivirus inhibitors by monoclonal antibodies. 2',3'-Isopropylideneuridine was also found to inhibit the replication of human immunodeficiency virus (HIV) in tissue culture by binding to the viral RNA polymerase and inhibiting its activity, preventing viral replication.
Chemical Properties
White Needle-Like Crystals
Uses
2′,3′-
O-Isopropylideneuridine is used in the chemical synthesis of
N-benzoylated uridine derivatives and
N3-substituted 2′,3′-
O-isopropylideneuridines with central nervous system (CNS) depressant activity.
Uses
2',3'-O-Isopropylideneuridine can be used as a useful precursor for the preparation of nucleic acids.