Description
Sodium methanesulfinate is an aliphatic sodium sulfinate. Conjugate addition of sodium methanesulfinate to vinyl heterocycles has been described. Cross-coupling reaction between aryl boronic acid and sodium methanesulfinate has been studied. It can be used in the preparation of alkyl methyl sulfone and methyl bis(4-tolyl)sulfoniumtrifluoromethanesulfonate. It is also employed in the synthesis of two sulfonyl type reversible addition-fragmentation transfer (RAFT) agents such as benzyl methylsulfonyldithioformate and benzyl phenylsulfonyldithioformate. Moreover, it can be used for synthesizing cyclooxygenase-2 inhibitors.
Chemical Properties
White to light beige powder
Uses
Sodium methylsulfinate can be used to synthesize cyclooxygenase-2 inhibitors.
General Description
Sodium methanesulfinate is an aliphatic sodium sulfinate. Conjugate addition of sodium methanesulfinate to vinyl heterocycles has been described. Cross-coupling reaction between aryl boronic acid and sodium methanesulfinate has been studied. Its stock solution was prepared from methanesulfonic acid by adding one equivalent of sodium hydroxide and diluting it to 4M.
