Uses
The enzyme from Sigma has been used in the digestion of phosphatidylserine fraction of
Schistosoma mansoni adult worms.
Uses
Phospholipase C from
Clostridium perfringens has been used as a positive control in sandwich enzyme linked immunosorbent assay (ELISA) and ELISA.
Uses
Phospholipase C (PLC) has been used to study adrenoceptor-mediated transmembrane signaling. It is also used to degrade inositol-containing phospholipids. Furthermore, it has been used to study
9E3 gene activation.
General Description
This product has been enhanced for energy efficiency and waste prevention when used in biodiesel research.
Biochem/physiol Actions
PLC hydrolyzes the phosphate bond on phosphatidylcholine and other glycerophospholipids yielding diacylglycerol. This enzyme also hydrolyzes the phosphate bonds of sphingomyelin, cardiolipin, choline plasmalogen and ceramide phospholipids. Phospholipase C is induced by thrombin and platelet-activating factor, forming 1,2-diacylglycerol and phosphatidic acid.