Description
Mca-DEVDAPK(Dnp)-OH is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-methoxycoumarin-4-acetyl (Mca), which can be used to quantify caspase-3 activity.
Uses
Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3[1].
References
[1] Fertig Georg. Method for the detection of the apoptosis activated cysteine protease Caspase 3 by specific antibody-binding and fluorescence enzyme assay. EP0955377A1
Sequene
Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH