6,8-Difluoro-7-hydroxy-4-methylcoumarin Structure

6,8-Difluoro-7-hydroxy-4-methylcoumarin

Chemical Properties

Melting point 213-215°C
Boiling point 332.3±42.0 °C(Predicted)
Density  1.494±0.06 g/cm3(Predicted)
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  Insoluble in water; soluble in chloroform, N,N-dimethylformamide, dimethyl sulfoxide
pka 4.7, (at 22℃) (calcd.) 5.50 ± 0.20, most acidic, temperature: 25 °C
form  Off-White to Pale Yellow Soild
color  Colorless needles; white solid
λmax 358 nm (Buffers pH 10.0, pH 9.0)
Stability Hygroscopic
Major Application Detecting/quantifying/measuring metals (beryllium, chromium, lead)
Biological Applications Amplifying/detectingnucleic acid sequences; analyzing peptides, sugarchains; detecting bacteria; detecting/quantifyingnucleic acids; a substrate for measuring acylprotein thioesterase (APT) activity,, α-amylaseactivity, aryl sulfatases activity, β-galactosidasesactivity,,, guanidinobenzoatase activity, β-lactamaseactivity, lipase activity, phosphatases activity,,phospholipase LYPLAL activity, protein kinasesactivity, xylanase activity; diagnosing/treatingtraumatic brain injury; treating amyloidogenic disease;as temperature sensor,
InChIKey LLENVBUPWUQAGL-UHFFFAOYSA-N
SMILES FC1=C2C(C(C)=CC(O2)=O)=CC(F)=C1O
UNSPSC Code 12352200
NACRES NA.21

Safety

Symbol(GHS) Skull and Crossbones (GHS06)
Signal wordDanger
Hazard statements H301-H317
Precautionary statements P261-P264-P272-P280-P301+P310-P302+P352
WGK Germany  WGK 3
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Skin Sens. 1

6,8-Difluoro-7-hydroxy-4-methylcoumarin Price

6,8-Difluoro-7-hydroxy-4-methylcoumarin Chemical Properties,Usage,Production

Preparation Products And Raw materials

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