H-Arg-Gln-OH hydrochloride salt
- Product NameH-Arg-Gln-OH hydrochloride salt
- CAS2483-17-2
- CBNumberCB6429890
- MFC11H22N6O4
- MW302.33
- MDL NumberMFCD06795767
- MOL File2483-17-2.mol
- MSDS FileSDS
Chemical Properties
| storage temp. | -15°C |
| Sequence | Arg-Gln |
H-Arg-Gln-OH hydrochloride salt Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| Biosynth FA108287 | 250mg | $292.5 | H-Arg-Gln-OH hydrochloride salt |
Buy |
| Biosynth FA108287 | 500mg | $505 | H-Arg-Gln-OH hydrochloride salt |
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| Biosynth FA108287 | 1000mg | $860 | H-Arg-Gln-OH hydrochloride salt |
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| Biosynth FA108287 | 2000mg | $1540 | H-Arg-Gln-OH hydrochloride salt |
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| Biosynth FA108287 | 5000mg | $3400 | H-Arg-Gln-OH hydrochloride salt |
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H-Arg-Gln-OH hydrochloride salt Chemical Properties,Usage,Production
Uses
Arginyl-Glutamine is a dipeptide that can decrease VEGF levels and inhibit retinal neovascularization in a mouse model of oxygen-induced retinopathy[1].Definition
ChEBI: Arg-Gln is a dipeptide formed from L-arginyl and L-glutamine residues. It has a role as a metabolite.in vivo
Arginyl-Glutamine (1-5 g/kg/day as a hydrochloride salt; i.p.; twice daily) dramatically inhibits retinal neovascularization in the mouse oxygen-induced retinopathy (OIR) model[1].
| Animal Model: | C57BL6/J mouse pups, oxygen-induced retinopathy (OIR) model[1] |
| Dosage: | 1.0, 2.5, or 5 g/kg per day |
| Administration: | Intraperitoneal injection, twice daily |
| Result: | Significantly decreased preretinal nuclei. Reduced neovascular tufts and vascular leakage in retinal vessels. Reduced preretinal neovascularization by 82% ± 7% and reduced VEGF mRNA by 64% ± 9% at 5 g/kg per day. |
References
[1] Neu J, et al. The dipeptide Arg-Gln inhibits retinal neovascularization in the mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2006 Jul;47(7):3151-5. DOI:10.1167/iovs.05-1473Preparation Products And Raw materials
Raw materials
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