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CYTOCHALASIN B

CYTOCHALASIN B Structure
CYTOCHALASIN B
  • CAS No.14930-96-2
  • Chemical Name:CYTOCHALASIN B
  • CBNumber:CB6323824
  • Molecular Formula:C29H37NO5
  • Formula Weight:479.61
  • MOL File:14930-96-2.mol
CYTOCHALASIN B Property
  • Melting point: :218-223 °C
  • Boiling point: :577.96°C (rough estimate)
  • Density  :1.1490 (rough estimate)
  • refractive index  :1.6290 (estimate)
  • Flash point: :85℃
  • storage temp.  :-20°C
  • solubility  :ethanol: 20 mg/mL
  • form  :powder
  • pka :13.60±0.70(Predicted)
  • color  :white
  • Merck  :13,2819
  • BRN  :1096207
  • InChIKey :UXVDBQLLXVKPRS-UZBFCAAUSA-N
  • FDA UNII :3CHI920QS7
  • EPA Substance Registry System :Cytochalasin B (14930-96-2)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H302-H330-H300+H310+H330-H361-H300-H310
  • Precautionary statements P301+P310a-P304+P340-P320-P330-P405-P501a-P260-P284-P310-P264-P280-P301+P310-P302+P350
CYTOCHALASIN B Price More Price(36)
  • Brand: Sigma-Aldrich
  • Product number: C2743
  • Product name : Cytochalasin B from Drechslera dematioidea
  • Purity: Ready Made Solution, 10mg/mL in DMSO, 0.2 μm filtered
  • Packaging: 200ul
  • Price: $122
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: C2743
  • Product name : Cytochalasin B from Drechslera dematioidea
  • Purity: Ready Made Solution, 10?mg/mL in DMSO, 0.2 μm filtered
  • Packaging: 200 μL
  • Price: $126
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 250233
  • Product name : Cytochalasin B,
  • Purity: 
  • Packaging: 5mg
  • Price: $161.87
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Alfa Aesar
  • Product number: J65342
  • Product name : Cytochalasin B
  • Purity: 
  • Packaging: 5mg
  • Price: $215
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Alfa Aesar
  • Product number: J65342
  • Product name : Cytochalasin B
  • Purity: 
  • Packaging: 10mg
  • Price: $371
  • Updated: 2021/12/16
  • Buy: Buy

CYTOCHALASIN B Chemical Properties,Usage,Production

  • Chemical Properties white to off-white powder
  • Uses Cytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin B exhibits potent inhibition of actin filament function leading to cell death by apoptosis, and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of this class display diverse selectivity. However, lack of comparative co-metabolite analysis has restricted a more complete understanding of their individual selectivity.
  • Uses A cell-permeable fungal toxin used in actin polymerization studies and cytological
  • Uses As tools in cytological research and in characterization of polymerization properties of actin, q.v.
  • Definition ChEBI: An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments.
  • Purification Methods Purify it by MeOH extraction, reverse phase C18 silica gel batch extraction by selective elution with 1:1 v/v hexane/tetrahydrofuran, crystallisation, subjected to TLC and recrystallisation [Lipski et al. Anal Biochem 161 332 1987]. It is soluble in EtOH (3.6%), Me2CO (1%), Me2SO (37%) and Me2NCHO (49%) at 24o, and can be crystallised from the first two solvents. It interferes with cellular movement [Korm Physiol Reviews 62 672 1982].
CYTOCHALASIN B Preparation Products And Raw materials
Raw materials
Preparation Products
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14930-96-2, CYTOCHALASIN BRelated Search:
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  • 3-d)isoindole-2,18(5h)-dione,16-benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-2h-oxacyclotetradec(
  • 7,20-dihydroxy-10-phenyl-5,16-dimethyl-24-oxa-[14]cytochalas-6(12),13,21-trien
  • Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem
  • (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione
  • Cytochalasin B (Phomin)
  • Cytochalasin B (Synonyms: Phomin)
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  • CYTOCHALASIN B FROM HELMINTHOSPORIUM DEMATIODEUM
  • (7S,13E,16R,20R,21E)-7,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,23-dione
  • (7S),(20R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione
  • PHOMIN
  • (7s,13e,16r,20r,21e)-0-phenyl
  • (e,e)-(5s,9r,12as,13s,15s,15as,16s,18as)-16-benzyl-6,7,8,9,10,12a,13,14,15,15a
  • ,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-,(e)-(
  • 9r,12as,13s,15s,15as,16as,18as)-5
  • 9r,12as,13s,15s,15as,16s,18as)--(5
  • Cytochalasin B, 98%, from Drechslera dematoidea
  • CYTOCHALASIN B FROM DRESCHSLERA DEMATIOIDEA
  • CYTOCHALASIN B SYNTHETIC >97%
  • CYTOCHALASIN B FROM DRESCHSLERA DEMATIOIDEA, BIOCHEMIKA, >= 95.0% (HPLC)
  • 2H-Oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione,6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-,(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-
  • CYTOCHALASIN B USP/EP/BP
  • 14930-96-2
  • C29H37NO5
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