Application
2-Hydroxy-6-methylpyridine is a heterocyclic organic compound with wide applications in organic synthesis. This product is basic and can catalyze the silylation of alcohols; it can also deprotect acetals.
Chemical Properties
white to cream-colored crystalline powder
Uses
2-Hydroxy-6-methylpyridine reacts with carboxylic acids RCOOH to give an equilibrium mixture of products M(2)(O(2)CR)(n)(mhp)(4-n) where R = 2-thienyl and phenyl. mhp is the anion formed from deprotonation of 2-hydroxy-6-methylpyridine
.
Synthesis Reference(s)
Journal of the American Chemical Society, 71, p. 1186, 1949
DOI: 10.1021/ja01172a014
General Description
2-Hydroxy-6-methylpyridine reacts with carboxylic acids RCOOH to give an equilibrium mixture of products M(2)(O(2)CR)(n)(mhp)(4-n) where R = 2-thienyl and phenyl. mhp is the anion formed from deprotonation of 2-hydroxy-6-methylpyridine.
