Description
Praziquantel-d
11 is intended for use as an internal standard for the quantification of praziquantel by GC- or LC-MS. Praziquantel is an anthelmintic agent. It is lethal to
S. mansoni schistosomula and adults (LC
50s = 0.68 and 0.03 mg/ml, respectively). Praziquantel (172 and 592 mg/kg) reduces worm burden in a mouse model of
S. mansoni infection. Formulations containing praziquantel have been used in the treatment of schistosomiasis.
Uses
As Labelled Praziquantel (P702095), Praziquantel-d11 can beused as Anthelmintic, effective against flatworms.
