Chemical Properties
storage temp. | Store at -80°C |
solubility | Soluble in DMSO |
FDA UNII | FU77B4U5Z0 |
NCI Drug Dictionary | ustekinumab |
ATC code | L04AC05 |
Ustekinumab Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Biosynth Carbosynth BU165596 | 1mg | $600 | Ustekinumab |
Buy |
ChemScene CS-7823 | 1mg | $828 | Ustekinumab 98.42% |
Buy |
ChemScene CS-7823 | 5mg | $2520 | Ustekinumab 98.42% |
Buy |
ChemScene CS-7823 | 25mg | $9500 | Ustekinumab 98.42% |
Buy |
ChemScene CS-7823 | 50mg | $15200 | Ustekinumab 98.42% |
Buy |
Ustekinumab Chemical Properties,Usage,Production
Description
Psoriasis is a chronic inflammatory skin disorder that affects approximately 2-3% of the world’s population. The most common form of the disease is plaque psoriasis, which is a result of dysregulated cell growth. Conventional treatment options for psoriasis include topical corticosteroids, phototherapy, and systemic drugs (oral retinoids, cyclosporine, and MTX), but all of these therapies have limitations. Ustekinumab is the latest biologic to be approved for the treatment of plaque psoriasis. It is a human IgG1k monoclonal antibody that binds with high affinity and specificity to the p40 protein subunit used by both the interleukin-12 (IL-12) and interleukin-23 (IL-23) cytokines. IL-12 and IL-23 are naturally occurring cytokines that are involved in inflammatory and immune responses, such as NK cell activation and CD4+ T-cell differentiation and activation. In in vitro models, ustekinumab is shown to disrupt IL12- and IL-23-mediated signaling and cytokine cascades by disrupting the interaction of these cytokines with a shared cell-surface receptor chain, IL-12?1. Ustekinumab is indicated for the treatment of adult patients (18 years or older) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.Adverse events associated with the use of ustekinumab included nasopharyngitis, upper respiratory tract infection, headache, fatigue, and diarrhea.
Originator
Medarex (US)Uses
Ustekinumab is used to treat plaque psoriasis, a certain type of arthritis or certain bowel conditions.brand name
StelaraPreparation Products And Raw materials
Ustekinumab Supplier
Global(76)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
+86-29-87569266 15319487004 |
1015@dideu.com | China | 2263 | 58 | |
+8613367258412 | ada@ipurechemical.com | China | 10326 | 58 | |
+86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 | |
86 18062405514 18062405514 |
ada@ipurechemical.com | CHINA | 3465 | 58 | |
+8617315815539 | sales@minbiotech.com | CHINA | 129 | 58 | |
+86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29016 | 58 | |
0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 | |
+8615604608665 15604608665 |
dominicguo@gk-bio.com | CHINA | 9427 | 58 | |
+8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 | |
0551-65418684 +8618949823763 |
sales@tnjchem.com | China | 25363 | 58 |
815610-63-0, UstekinumabRelated Search
PROMPT×
PROMPT
The What'sApp is temporarily not supported in mainland China
The What'sApp is temporarily not supported in mainland China
Cancel
Determine