ipilimumab
- Product Nameipilimumab
- CAS477202-00-9
- CBNumberCB72498811
- MW0
- MDL NumberMFCD01864202
- MOL FileMol file
Chemical Properties
NCI Dictionary of Cancer Terms | ipilimumab |
FDA UNII | 6T8C155666 |
NCI Drug Dictionary | ipilimumab |
ATC code | L01XC11 |
ipilimumab Chemical Properties,Usage,Production
Description
Ipilimumab is a CTLA-4 blocking antibody that was approved by the U.S. FDA in March 2011 for the treatment of unresectable or metastatic melanoma. Therefore, ipilimumab has an indirect effect on tumors that is mediated through blockade of CTLA-4 negative signaling and augmentation of T-cell activity. It is one of a handful of immunostimulatory drugs (e.g., aldesleukin and interferon alfa-2b) now approved for cancer therapy.Originator
Bristol-Myers Squibb (United States)Uses
Treatment of oncology disease and HIV infection.brand name
YervoyClinical Use
Antineoplastic agent:Treatment of advanced (unresectable or metastatic) melanoma in adults who have received prior therapy
Drug interactions
Potentially hazardous interactions with other drugsLive vaccines: risk of generalised infections - avoid.
Metabolism
Most likely removed by opsonisation via the reticuloendothelial system when bound to T lymphocytes, or by human antimurine antibody production.Preparation Products And Raw materials
ipilimumab Supplier
Global(69)Suppliers
Supplier | Tel | Country | ProdList | Advantage | ||
---|---|---|---|---|---|---|
+8617315815539 | sales@minbiotech.com | CHINA | 129 | 58 | ||
+8613367258412 | ada@ipurechemical.com | China | 10326 | 58 | ||
+86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 | ||
86 18062405514 18062405514 |
ada@ipurechemical.com | CHINA | 3465 | 58 | ||
0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 | ||
+86-27-59207850 +86-13986145403 |
info@fortunachem.com | China | 5981 | 58 | ||
+8615604608665 15604608665 |
dominicguo@gk-bio.com | CHINA | 9427 | 58 | ||
+8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 | ||
+8615389281203 | maria@goltbiotech.com | China | 980 | 58 | ||
+undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
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