pseudolycorine

Description

Pseudolycorine can halt HeLa cell growth at 10-1 mM or lower concentrations, it at its growth inhibitory concentrations blocks protein synthesis in ascites cells and stabilize HeLa cell polysomes in vivo. Pseudolycorine exhibits cytotoxic profiles against cancer cell lines. 3. Pseudolycorine and haemanthamine show good activity in in vitro assays against Trypanosoma brucei rhodesiense, T. cruzi and Plasmodium falciparum with IC50 values in the range of 3.66 uM or lower. 4. Pseudolycorine, primarily studied as a new antiviral agent , it also shows remarkable antileukemic activity.

Definition

ChEBI: Pseudolycorine is a member of phenanthridines.

target

Antifection | DNA/RNA Synthesis