Description
N-Desmethylclobazam (CRM) (Item No. 18888) is a certified reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4. N-Desmethylclobazam (CRM) positively modulates GABA
A receptors (EC
50s range from 98 to 151 μM, depending on subunit configuration). This product is intended for research and forensic applications.
Description
N-Desmethylclobazam (Item No. 18564) is an analytical reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4. N-Desmethylclobazam positively modulates GABA
A receptors (EC
50s range from 98 to 151 μM, depending on subunit configuration). This product is intended for research and forensic applications.
Chemical Properties
Off-White Solid
Uses
The major metabolite of Clobazam
Controlled substance (depressant).
Definition
ChEBI: N-Desmethylclobazam is a benzodiazepine.
General Description
A Certified Solution Standard for use in LC or GC applications from forensic and forensic toxicology analysis to urine drug testing. N-Desmethylclobazam, found in urine, serum, and plasma, is the pharmacologically active, major metabolite of clobazam.
